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Screening of extracts of Japanese medicinal plants for HMG-CoA reductase inhibition
http://hdl.handle.net/10232/00004447
http://hdl.handle.net/10232/000044476f5c2cd5-da1d-4257-822e-e1ec835a02fa
名前 / ファイル | ライセンス | アクション |
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6.pdf (175.2 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2015-01-07 | |||||
タイトル | ||||||
タイトル | Screening of extracts of Japanese medicinal plants for HMG-CoA reductase inhibition | |||||
別言語のタイトル | ||||||
その他のタイトル | HMG-CoAレダクターゼ阻害活性を有する生薬抽出物のスクリーニング | |||||
著者 |
横山, 聡
× 横山, 聡× 竹野, 明香× 永田, 敏郎× 清水, 邦義× 近藤, 隆一郎 |
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別言語の著者 | ||||||
姓名 | Yokoyama, Satoru | |||||
別言語の著者 | ||||||
姓名 | Takeno, Sayaka | |||||
別言語の著者 | ||||||
姓名 | Nagata, Toshiro | |||||
別言語の著者 | ||||||
姓名 | Shimizu, Kuniyoshi | |||||
別言語の著者 | ||||||
姓名 | Kondo, Ryuichiro | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ヨモギ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | トウジュロ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HMG-CoAレダクターゼ | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 抗高脂血症 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | 高脂血症 | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | Artemisia princeps | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | Trachycarpus wagnerianus | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | Hyperlipidemia | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase | |||||
キーワード | ||||||
主題言語 | en | |||||
主題Scheme | Other | |||||
主題 | Antihyperlipidemia | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | Aqueous, methanol, ethanol or dichloromethane extracts of 22 medicinal plants were examined for their inhibitory activity on 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. The samples which showed more than 80 % inhibition at the concentration of 1,000 pg/ml were selected as the potential HMG-CoA reductase inhibitory ingredients. The aqueous extract of herbal part of Artemisia princeps and the ethanol extract of fruit/seeds of Trachycarpus wagnerianus were selected and showed HMG-CoA reductase inhibitory activity with 88.1 ± 3.2 % and 83.7 ± 0.3 % at 1,000 pg/ml, respectively. | |||||
要約(Abstract) | ||||||
内容記述タイプ | Other | |||||
内容記述 | 生薬として用いられている薬用植物22種類を水,メタノール,エタノール,ジクロロメタンで抽出し,各抽出物の3-hydroxy-3-methylglutaryl coenzyme A(HMG-CoA)レダクターゼ阻害活性を測定した。抽出物濃度1,111_/mlで80%以上の阻害活性を有する試料を選抜した結果,Artemisia princepsとTrachycarpus wagnerianusがHMG-CoAレダクターゼ阻害成分を含む試料として見出された。Artemisia princepsの全草の水抽出物とTrachycarpus wagnerianusの果実と種子の混合物のエタノール抽出物は,抽出物濃度1,111_/mlの試験でそれぞれ88.1±3.2%と83.7±0.3%のHMG-CoAレダクターゼ阻害活性を示した。 | |||||
収録雑誌名 |
鹿児島大学農学部演習林研究報告 en : Research bulletin of the Kagoshima University forests 巻 37, p. 37-41 |
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作成日 | ||||||
日付 | 2010-03-01 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
ISSN | 13449362 | |||||
NII書誌ID(雑誌) | ||||||
収録物識別子タイプ | NCID | |||||
NC ID | AN10592752 | |||||
出版タイプ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
NDC | ||||||
主題Scheme | NDC | |||||
主題 | 499 | |||||
公開者・出版者 | ||||||
出版者 | 鹿児島大学 | |||||
公開者よみ | ||||||
公開者よみ | カゴシマ ダイガク | |||||
公開者別名 | ||||||
公開者別名 | Kagoshima University | |||||
旧URI | ||||||
旧URI | http://hdl.handle.net/10232/10259 |