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Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks Ijiri, Daichi イジリ, ダイチ 井尻, 大地 Higuchi, Asami Saegusa, Akito Miura, Moe Matsubara, Tomoko Kanai, Yukio Ohtsuka, Akira オオツカ, アキラ 大塚, 彰 Hirabayashi, Miho open access Elsevier Cold adaptation Cold tolerance Muscle growth Prolactin-like protein Thermogenesis This study examined the hypothesis that a novel prolactin-like protein gene (PRL-L) is involved in cold-induced growth of skeletal muscle in chicks. Six-day-old chicks (Gallus gallus domesticus) were exposed to cold at 4 °C or kept warm at 30 °C for 24 h. Cold exposure induced significant increases in PRL-L expression that coincided with increases in the weight of the sartorius muscle, which comprises both fast- and slow-twitch fibers. Meanwhile, no induction of PRL-L mRNA was observed in the heart, liver, kidney, brain, or fat. Myoblast cells that expressed PRL-L mRNA grew faster than untransduced cells in media containing 2% serum. These results suggested that PRL-L might be involved in in controlling cold-induced muscle growth of chicks. Elsevier 2013 eng journal article AM http://hdl.handle.net/10232/18562 https://ir.kagoshima-u.ac.jp/records/982 23523997 https://doi.org/10.1016/j.ygcen.2013.03.007 00166480 AA00654410 General and Comparative Endocrinology 186 94 100 https://ir.kagoshima-u.ac.jp/record/982/files/IJIRI_Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks.pdf application/pdf 1.6 MB 2016-10-27 2013-06-01