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Distinguishing adrenal adenomas from non-adenomas on dynamic enhanced CT: A comparison of 5 and 10 min delays after intravenous contrast injection 副腎腫瘍に対するダイナミックCTにおける至適後期相撮像タイミングの検討 熊谷, 雄一 クマガエ, ユウイチ Kumagae, Yuichi open access 博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨 Aim: To evaluate the usefulness of several parameters of 5 min compared to 10 min delayed contrast-enhanced CT in distinguishing adenomas from non-adenomas. Materials and methods: The study population consisted of 94 patients (52 men and 42 women; mean age 62 years) with 103 adrenal lesions (75 adenomas and 28 non-adenomas). In each patient, unenhanced CT was followed by early, 5 and 10 min enhanced CT. Diagnostic parameters included delayed enhanced attenuation at 5 and 10 min, washout attenuation (WO) at 5 and 10 min, absolute percentage washout (APW) at 5 and 10 min, and relative percentage washout (RPW) at 5 and 10 min. The accuracy of each parameter for diagnosing adenomas from non-adenomas was calculated using receiver operating characteristic (ROC) analysis. Results: Upon comparison between 5 and 10 min delayed contrast-enhanced CT for differentiating total adenomas or lipid-poor adenomas from non-adenomas, there was no significant difference in the area under the binomial ROC curve (Az) values of delayed enhanced attenuation (total adenomas versus non-adenomas, p = 0.164; lipid-poor adenomas versus non-adenomas, p = 0.178), WO (total adenomas versus non-adenomas, p = 0.216; lipid-poor adenomas versus non-adenomas, p = 0.230), APW (total adenomas versus non-adenomas, p = 0.401; lipid-poor adenomas versus non-adenomas, p = 0.870), or RPW (total adenomas versus non-adenomas, p = 0.160; lipid-poor adenomas versus non-adenomas, p = 0.780). Conclusion: Five minute contrast-enhanced CT was as useful as 10 min contrast-enhanced CT for differentiation of adrenal adenomas from non-adenomas. Y. Kumagae, Y. Fukukura, K. Takumi, T. Shindo, A. Tateyama, T. Kamiyama, K. Kamimura, M. Nakajo Distinguishing adrenal adenomas from non-adenomas on dynamic enhanced CT: A comparison of 5 and 10 min delays after intravenous contrast medium injection Clinical Radiology 68 (2013) 696-703 https://doi.org/10.1016/j.crad.2013.01.016 Elsevier 鹿児島大学 eng doctoral thesis VoR http://hdl.handle.net/10232/26480 https://ir.kagoshima-u.ac.jp/records/12082 甲総研第355号 博士(医学) Doctor of Philosophy in Medical Science 2016-03-17 17701 鹿児島大学 https://ir.kagoshima-u.ac.jp/record/12082/files/Diss_熊谷_雄一_ISK355_2016.pdf application/pdf 929.3 kB 2023-03-13 2016-01-01 https://ir.kagoshima-u.ac.jp/record/12082/files/Abstract_熊谷_雄一_454810331_2015.pdf application/pdf 80.3 kB 2018-07-20 2016-01-01 https://ir.kagoshima-u.ac.jp/record/12082/files/Result_Kumagae_Yuichi_isk355_2015.pdf application/pdf 105.8 kB 2016-10-31 2016-01-01 https://ir.kagoshima-u.ac.jp/record/12082/files/Comments_Kumagae_Yuichi_isk355_2015.pdf application/pdf 61.4 kB 2016-10-31 2016-01-01