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Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks Ijiri, Daichi 121677 イジリ, ダイチ 井尻, 大地 Higuchi, Asami 121678 Saegusa, Akito 121679 Miura, Moe 121680 Matsubara, Tomoko 121681 Kanai, Yukio 121682 Ohtsuka, Akira 121683 オオツカ, アキラ 大塚, 彰 Hirabayashi, Miho 121684 481 Cold adaptation Cold tolerance Muscle growth Prolactin-like protein Thermogenesis This study examined the hypothesis that a novel prolactin-like protein gene (PRL-L) is involved in cold-induced growth of skeletal muscle in chicks. Six-day-old chicks (Gallus gallus domesticus) were exposed to cold at 4 °C or kept warm at 30 °C for 24 h. Cold exposure induced significant increases in PRL-L expression that coincided with increases in the weight of the sartorius muscle, which comprises both fast- and slow-twitch fibers. Meanwhile, no induction of PRL-L mRNA was observed in the heart, liver, kidney, brain, or fat. Myoblast cells that expressed PRL-L mRNA grew faster than untransduced cells in media containing 2% serum. These results suggested that PRL-L might be involved in in controlling cold-induced muscle growth of chicks. journal article Elsevier 2013 AM application/pdf General and Comparative Endocrinology 186 94 100 00166480 AA00654410 https://ir.kagoshima-u.ac.jp/record/982/files/IJIRI_Role of prolactin-like protein (PRL-L) in cold-induced increase of muscle mass in chicks.pdf http://hdl.handle.net/10232/18562 https://ir.kagoshima-u.ac.jp/records/982 eng 23523997 https://doi.org/10.1016/j.ygcen.2013.03.007 Elsevier open access