{"created":"2023-07-25T08:10:40.430325+00:00","id":10653,"links":{},"metadata":{"_buckets":{"deposit":"80142a1a-84f8-45fd-a057-fba3085dda89"},"_deposit":{"created_by":18,"id":"10653","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"10653"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00010653","sets":["43:81"]},"author_link":["96461"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-03-31","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2009-2010年度科学研究費補助金(研究活動スタート支援)研究成果報告書 課題番号：21880038　研究代表者：白藤梨可 (鹿児島大学農学部プロジェクト研究員)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"獣医・医学上重要な吸血性節足動物マダニについて、数年に及ぶ生活史の大半を未吸血・飢餓状態で過ごすという性質に着目し、マダニの飢餓耐性を担う分子基盤の解明を実施した。未吸血マダニにおけるオートファジー関連遺伝子群の発現抑制ならびにオートファジー阻害剤処理により、実験群のマダニにおいて寿命が短縮した。このことから、宿主探索時のマダニはオートファジーを活用して栄養分を補い、飢餓に耐えていることが示唆された。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"Ticks are hematophagous arthropods and they can survive without food during the host-seeking period for several months to years. This study focused on autophagy which is induced during starvation in eukaryotes. Knockdown of autophagy-related genes and treatment with autophagy inhibitor led to a shortened life span in adult ticks. Tick autophagy might help compensate for the loss of nutrients derived from host blood components during the non-feeding period.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"649","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"21880038"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"白藤, 梨可","creatorNameLang":"ja"},{"creatorName":"シラフジ, リカ","creatorNameLang":"ja-Kana"},{"creatorName":"SHIRAFUJI, Rika","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"21880038seika.pdf","filesize":[{"value":"366.2 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"21880038seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/10653/files/21880038seika.pdf"},"version_id":"d8425a9e-c004-4826-af7c-91c694e51267"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"マダニ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"オートファジー","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"オートファジー関連遺伝子","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"飢餓","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"寿命","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Target of rapamycin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ビテロジェニン","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"マダニにおけるオートファジーの分子機構の解明とその制御因子の同定","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"マダニにおけるオートファジーの分子機構の解明とその制御因子の同定","subitem_title_language":"ja"},{"subitem_title":"Study on the molecular mechanism of autophagy at nonfeeding periods in the hard tick Haemaphysalis longicornis","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["81"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"10653","relation_version_is_last":true,"title":["マダニにおけるオートファジーの分子機構の解明とその制御因子の同定"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-04-24T07:02:52.381880+00:00"}