{"created":"2023-07-25T08:11:02.053920+00:00","id":11117,"links":{},"metadata":{"_buckets":{"deposit":"b49faa5e-1b08-40eb-8bb6-550dc2716a8b"},"_deposit":{"created_by":3,"id":"11117","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"11117"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011117","sets":[]},"author_link":["74423","74422","52720"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of infection mechanism of culture-negative endocarditis"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"キエンキン フメイ ト サレテキタ カンセンセイ シンナイマクエン ノ カンセン キジョ ノ カイメイ オヨビ シンキ ヨボウホウ ノ カイハツ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-30"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2009-2011年度科学研究費助成事業(科学研究費補助金(若手研究(B)))研究成果報告書　課題番号：21792155　研究代表者：五月女さき子 (鹿児島大学医学部・歯学部附属病院助教)","subitem_description_type":"Other"},{"subitem_description":"Granulicatella adiacens表層にあるフィブロネクチン結合タンパク質Chaを同定した。Chaは相同性の高いStreptococcus gordonii DL1のcshAの2351アミノ酸残基を持ち、N末端側はユニークな配列、C末端領域は9個と1つの不完全な115アミノ酸残基の繰り返し領域からなる。他の4菌種においてもFn結合能を示したが、その強さはCha遺伝子の存在とは直接の関係がみられなかった。しかしN末領域および繰り返し領域ともよく保存されていた。","subitem_description_type":"Other"},{"subitem_description":"Granulicatella adiacens is a member of the oral microbiota, formerly known as nutritionally variant streptococci, and is often isolated from endocarditis patients. In the present study we identified a surface protein, designated Cha, which binds to fibronectin, by a plaque hybridization procedure using the cshA sequence as probe, which encodes a fibronectin-binding molecule of Streptococcus gordonii DL1. The cha sequence was highly homologous to cshA and encoded a product of 2351 amino acid residues. The protein comprised a unique sequence in the N-terminal half region. The C-terminal region contained nine complete, and one incomplete, 115-amino acid residue repeat blocks. Among eight strains of nutritionally variant streptococci, three G. adiacens strains and one Abiotrophia defectiva strain carried the cha gene.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ソウトメ, サキコ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"SOUTOME, Sakiko"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"21792155"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"五月女, さき子"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"21792155seika.pdf","filesize":[{"value":"389.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"21792155seika.pdf","url":"https://ir.kagoshima-u.ac.jp/record/11117/files/21792155seika.pdf"},"version_id":"87d7d6ba-8106-44cb-ad71-d5cbe62e71e5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"レンサ球菌","subitem_subject_scheme":"Other"},{"subitem_subject":"フィブロネクチン","subitem_subject_scheme":"Other"},{"subitem_subject":"モノクローナル抗体","subitem_subject_scheme":"Other"},{"subitem_subject":"心内膜炎","subitem_subject_scheme":"Other"},{"subitem_subject":"Granulicatella adiacens","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"起炎菌不明とされてきた感染性心内膜炎の感染機序の解明および新規予防法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"起炎菌不明とされてきた感染性心内膜炎の感染機序の解明および新規予防法の開発"}]},"item_type_id":"8","owner":"3","path":["83"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-12-22"},"publish_date":"2014-12-22","publish_status":"0","recid":"11117","relation_version_is_last":true,"title":["起炎菌不明とされてきた感染性心内膜炎の感染機序の解明および新規予防法の開発"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-01-29T08:29:05.744725+00:00"}