{"created":"2023-07-25T08:11:02.271822+00:00","id":11122,"links":{},"metadata":{"_buckets":{"deposit":"c1217909-b08b-42f7-b0e0-045f8719d51e"},"_deposit":{"created_by":18,"id":"11122","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"11122"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011122","sets":["43:81"]},"author_link":["52733"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-31","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2010-2011年度科学研究費助成事業(科学研究費補助金(若手研究(B)))研究成果報告書　課題番号：22780283　研究代表者：三浦直樹 (鹿児島大学農学部准教授)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"イヌ腫瘍のmicroRNA特異的発現パターンの観察と分子マーカーとしての可能性を目的として、病理学的に確定診断されたイヌ腫瘍におけるmicroRNAの発現プロファイルを検討した。microRNAアレイ（miRCURY Array microRNA：イヌのmicroRNA配列を含む）を用いて7種類の腫瘍について発現解析を行い、今回、特に乳腺腫瘍や悪性黒色腫で特異的に変動するmicroRNAを選出した。選出されたmicroRNAについてqRT-PCRで発現変化を確認した。更に乳腺腫瘍罹患イヌの血清中でmiR-21と92aの上昇を確認した。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"A few novel microRNAs, which was up- or down- regulated in either mammary gland tumor or melanoma, were identified by the canine micro RNA microarray. The differential expression of these microRNAs was confirmed by quantitative RT-PCR. We also found that miR-21 and miR-92a had been significantly higher existing in the plasma from dog with mammary gland tumor compared to clinically healthy dog.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"649","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"22780283"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"三浦, 直樹","creatorNameLang":"ja"},{"creatorName":"ミウラ, ナオキ","creatorNameLang":"ja-Kana"},{"creatorName":"MIURA, Naoki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"52733","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000080508036","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"22780283seika.pdf","filesize":[{"value":"323.0 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"22780283seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/11122/files/22780283seika.pdf"},"version_id":"ce58f9ec-1d85-448b-b2c0-8d0ab7b8ca83"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"イヌ","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"microRNA","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"腫瘍","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"疾患マーカー","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"イヌ腫瘍の新規診断マーカーmicroRNAの探索に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"イヌ腫瘍の新規診断マーカーmicroRNAの探索に関する研究","subitem_title_language":"ja"},{"subitem_title":"MicroRNA expression in the canine tumor","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["81"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-12-22"},"publish_date":"2014-12-22","publish_status":"0","recid":"11122","relation_version_is_last":true,"title":["イヌ腫瘍の新規診断マーカーmicroRNAの探索に関する研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-04-24T07:02:49.351864+00:00"}