{"created":"2023-07-25T08:11:02.356631+00:00","id":11124,"links":{},"metadata":{"_buckets":{"deposit":"abf04664-431b-448e-aeab-cb12270723ac"},"_deposit":{"created_by":18,"id":"11124","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"11124"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011124","sets":["82:83"]},"author_link":["52739"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-31","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2010-2011年度科学研究費助成事業(科学研究費補助金(若手研究(B)))研究成果報告書　課題番号：22791673　研究代表者：内野英輔 (鹿児島大学医学部・歯学部附属病院助教)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"drug deliveryやgene transferの手段として超音波にmicro bubbleやbubble liposomeを併用することでより効率的に遺伝子や薬物の導入が可能になった。その効果を定量的に評価することを目的として研究を行った。既にin vitroで得られた至適条件とほぼ同様の超音波照射条件が薬物、遺伝子の細胞内の取り込みに適していることがわかった。また眼組織の超音波照射に最適なプローブの形状に関する知見を得た。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"By using ultrasonic irradiation with microbubbles uptakes of materials into cells increase than ultrasonic irradiation alone. Our aim is to evaluate the efficacy of ultrasonic irradiation to anterior ocular segment. We found optimal conditions of ultrasonic irradiation in vitro / in vivo, and suitable shape of ultrasonic probe.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"496","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"22791673"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内野, 英輔","creatorNameLang":"ja"},{"creatorName":"UCHINO, Eisuke","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"52739","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000020398275","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"22791673seika.pdf","filesize":[{"value":"164.4 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"22791673seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/11124/files/22791673seika.pdf"},"version_id":"a2f12276-ffed-41bf-a417-8d0165f752f0"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"薬理学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"マイクロ・ナノデバイス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"超音波","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"リポソームを併用した前眼部への遺伝子導入・薬物送達法の評価法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"リポソームを併用した前眼部への遺伝子導入・薬物送達法の評価法の開発","subitem_title_language":"ja"},{"subitem_title":"Evaluation of gene transfer and drug delivery with liposome to anterior segment of eyes","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["83"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-05-14"},"publish_date":"2015-05-14","publish_status":"0","recid":"11124","relation_version_is_last":true,"title":["リポソームを併用した前眼部への遺伝子導入・薬物送達法の評価法の開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-06-10T05:23:22.479279+00:00"}