@article{oai:ir.kagoshima-u.ac.jp:00011184,
 author = {板倉, 英世},
 journal = {南方海域調査研究報告=Occasional Papers},
 month = {2016-10-31},
 note = {There are a lot of liver diseases in the tropics. Yellow fever is one of viral
hemorrhagic fevers which exert influence upon the liver. Midzonal necrosis and
Councilman body are characteristic histological features of the liver. Hemorrhagic fevers such as Lassa fever, Marburg virus disease and Ebola hemorrhagic fever show more or less irregular degenerative and necrotic changes of liver parenchymal cells with relatively slight inflammatory cell infiltration. Characteristic bile stasis of peripheral region of liver lobules and foamy degeneration of liver parenchymal cells are observed in the liver in Hemorrhagic Fever with Renal Syndrome (Korean Hemorrhagic Fever). Dengue Hemorrhagic Fever and Rift Valley fever also affect the liver.
Although malaria itself is not liver disease, remarkable mobilization of Kupffer
calls containing malarial parasites is observed occasionally. In experimental malaria using mice, scattered acidophilic necrosis of liver parenchymal cells is seen. In chronic malaria, probably tertian malaria, liver usually shows only deposition of malarial pigments in some Kupffer cells with no or very slight parenchymal lesion
or fibrosis. In visceral Leishmaniasis, Kala-azar, parasites could be seen in
not only Kupffer cells but also liver parenchymal cells.
Pericholangiolar inflammatory cell infiltration and fibrosis of the liver occur
in clonorchiasis and fascioliasis, because the parasites infect bile system of the
liver. Unilocular echinoccosis is seen in Africa and other tropical areas. Large
cyst formation cause mechanical disturbance of the liver. Schistosomiasis japonica
and mansoni are prevalent in tropical areas, and fibrosis or cirrhosis of the liver
can be observed.
Mycotoxicosis especially acute aflatoxicosis is sometimes reported in tropical
areas. Whether mycotoxins play etiological role of primary hepatocellular carcinoma
of man is not known. Reye's syndrome and kwashiorkor are related to nutritional
disturbances or malnutrition showing fatty metamorphosis of liver parenchymal cells. In Bantu siderosis, diffuse iron deposition is observed in the liver both in
Kupffer cells and liver parenchymal cells. Iron overload through oral intake is
considered as etiology.
Viral hepatitis A, viral hepatitis B and non-A, non-B hepatitis are also
prevalent in the Tropics., 板倉英世（長崎大学熱帯医学研究所病理学部門）},
 pages = {49--60},
 title = {熱帯地における主なウイルス性出血熱,原虫感染症,中毒性疾患の肝臓病変},
 volume = {6},
 year = {}
}