@article{oai:ir.kagoshima-u.ac.jp:00011243,
 author = {KITANO, Motoo},
 journal = {南太平洋海域調査研究報告=Occasional papers},
 month = {2016-10-31},
 note = {Recent studies concerning the pathogenesis of decompression sickness (DCS) were reviewed. Discussion of the related evidence linking the observations of pathological findings in human beings and experimental animals with acute DCS leads us to conclude that the acute
elevation of tissue pressure inside a compartment such as a bone marrow cavity which is encased by rigid cortical bone, following acute decompression of atmospheric pressure is most responsible for the development and progression of tissue damage in DCS. The brain
and the spinal cord are also located within compartments which are encased by a rigid dural membrane with or without an overlying rigid bone. A high incidence of damage of all of these three organs is seen in patients with acute DCS. However, the severity of tissue damage
is not equally distributed throughout a compartment, and cannot be understood only by this etiology. Instead, "watershed zones" may explain the site predisposition of tissue damage in
each organ. "Watershed zones" are the most vulnerable areas where the arterioles and arteries may easily collapse due to the acute increase of the perivascular tissue pressure.
Abnormalities of the venous vessels are widely observed in these three organs in DCS,
which are characterized by many nitrogen gas bubble emboli, fat emboli and thrombi in the
venous system. These abnormalities in the venous system should cause disturbances in venous blood circulation. Disturbance in venous blood returning towards the heart from these organs should accentuate the elevation of the tissue pressure inside the compartments. The
disturbance of the venous system may not be the last word when discussing the pathogenesis of tissue damage in DCS, but it should be considered in any further research on this subject.},
 pages = {47--59},
 title = {Pathological Aspects of Decompression Sickness},
 volume = {25},
 year = {}
}