{"created":"2023-07-25T08:11:08.684776+00:00","id":11269,"links":{},"metadata":{"_buckets":{"deposit":"4eb3a4de-fcc0-4754-b4d4-16b5b5ae8120"},"_deposit":{"created_by":18,"id":"11269","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"11269"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011269","sets":["54:92"]},"author_link":["115113","115114","115115","115116","115117"],"item_6_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1963","bibliographicPageEnd":"2492","bibliographicPageStart":"2485","bibliographicVolumeNumber":"277","bibliographic_titles":[{"bibliographic_title":"Proceedings of the Royal Society. B, Biological sciences","bibliographic_titleLang":"en"}]}]},"item_6_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2010-08-22","subitem_date_issued_type":"Issued"}]},"item_6_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"The recent discovery of melanopsin-containing retinal ganglion cells (mRGCs) has led to a fundamental reassessment of non-image forming processing, such as circadian photoentrainment and the pupillary light reflex. In the conventional view of retinal physiology, rods and cones were assumed to be the only photoreceptors in the eye and were, therefore, considered responsible for non-image processing. However, signals from mRGCs contribute to this non-image forming processing along with cone-mediated luminance signals; although both signals contribute, it is unclear how these signals are summed. We designed and built a novel multi-primary stimulation system to stimulate mRGCs independently of other photoreceptors using a silent-substitution technique within a bright steady background. The system allows direct measurements of pupillary functions for mRGCs and cones. We observed a significant change in steady-state pupil diameter when we varied the excitation of mRGC alone, with no change in luminance and colour. Furthermore, the change in pupil diameter induced by mRGCs was larger than that induced by a variation in luminance alone: that is, for a bright steady background, the mRGC signals contribute to the pupillary pathway by a factor of three times more than the L- and M-cone signals.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_6_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"The Royal Society","subitem_publisher_language":"en"}]},"item_6_relation_10":{"attribute_name":"PubMedId","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"20375057","subitem_relation_type_select":"PMID"}}]},"item_6_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1098/rspb.2010.0330","subitem_relation_type_select":"DOI"}}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09628452","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11210011","subitem_source_identifier_type":"NCID"}]},"item_6_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_6_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"Definitive Published Version is available at: http://rspb.royalsocietypublishing.org/"}]},"item_6_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tsujimura, Sei-ichi","creatorNameLang":"en"},{"creatorName":"ツジムラ, セイイチ","creatorNameLang":"ja-Kana"},{"creatorName":"辻村, 誠一","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ukai, Kazuhiko","creatorNameLang":"en"},{"creatorName":"ウカイ, カズヒコ","creatorNameLang":"ja-Kana"},{"creatorName":"鵜飼, 一彦","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohama, Daisuke","creatorNameLang":"en"},{"creatorName":"オオハマ, ダイスケ","creatorNameLang":"ja-Kana"},{"creatorName":"大濱, 大輔","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Nuruki, Atsuo","creatorNameLang":"en"},{"creatorName":"ヌルキ, アツオ","creatorNameLang":"ja-Kana"},{"creatorName":"塗木, 淳夫","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yunokuchi, Kazutomo","creatorNameLang":"en"},{"creatorName":"ユノクチ, カズトモ","creatorNameLang":"ja-Kana"},{"creatorName":"湯ノ口, 万友","creatorNameLang":"ja"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"Tsujimura_Manuscript_Proc.R.Soc.B_v277n1693_p2485-2492.pdf","filesize":[{"value":"484.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Tsujimura_Manuscript_Proc.R.Soc.B_v277n1693_p2485-2492.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/11269/files/Tsujimura_Manuscript_Proc.R.Soc.B_v277n1693_p2485-2492.pdf"},"version_id":"eb4c1534-8ed4-4ecc-b76c-0406bd2da22b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"melanopsin ganglion cells","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"silent substitution","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pupil","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"four-primary stimulation","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Contribution of human melanopsin retinal ganglion cells to steady-state pupil responses","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Contribution of human melanopsin retinal ganglion cells to steady-state pupil responses","subitem_title_language":"en"}]},"item_type_id":"6","owner":"18","path":["92"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2013-02-01"},"publish_date":"2013-02-01","publish_status":"0","recid":"11269","relation_version_is_last":true,"title":["Contribution of human melanopsin retinal ganglion cells to steady-state pupil responses"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-02-07T07:19:47.786040+00:00"}