{"created":"2023-07-25T08:11:24.278565+00:00","id":11590,"links":{},"metadata":{"_buckets":{"deposit":"70b58847-707a-479d-8ca3-feaedf1fb67d"},"_deposit":{"created_by":3,"id":"11590","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"11590"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011590","sets":[]},"author_link":["47488","112865","112864"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of capillary-like network for creating three-dimensional tissues"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"セイタイ ト ルイジ ノ モウサイケッカンモウ オヨビ サイセイ イリョウヨウ ジュウコウ サンジゲン ゾウキ ソウセイ ギジュツ ノ カイハツ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-05-31"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2011-2012年度科学研究費助成事業(科学研究費補助金(若手研究(B))研究成果報告書　課題番号：23760752　研究代表者：武井孝行(鹿児島大学・大学院理工学研究科・准教授)","subitem_description_type":"Other"},{"subitem_description":"ポリメタクリル酸メチル（PMMA）からなる直径10μm程度のファイバーを調製した。そのファイバーの束をアガロースゲル内に包埋し、ファイバーのみを特異的に溶解することで、ゲル内に毛細血管網様流路ネットワークを作製した。続いて、多孔質化したそのゲルに肝癌細胞を播種後、その多孔質体をアガロースゲルで密閉した。多孔質体の流路内部に培地を流通させながら培養することで、培地を流通させなかった条件よりも、より多くの生細胞を多孔質体内部に保持できることが示唆された。","subitem_description_type":"Other"},{"subitem_description":"Poly(methyl methacrylate)(PMMA)microfibers of approximately 10 μm in diameter were prepared using wet spinning technique. The microfibers were embedded in agarose gel and dissolved specifically, resulting in formation of capillary-like network in the gel. The gel was freeze-dried and hepatoblastoma was seeded into the sponge-like gel. Then, the sponge was coated with agarose gel. Culture medium was perfused into the capillary-like network in the sponge. Albumin productivity of the sponge with perfusion of medium was higher than that without medium perfusion.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"タケイ, タカユキ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"TAKEI, Takayuki"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491.3","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"23760752"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"武井, 孝行"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"23760752.pdf","filesize":[{"value":"360.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"23760752.pdf","url":"https://ir.kagoshima-u.ac.jp/record/11590/files/23760752.pdf"},"version_id":"544087bb-a6f0-4340-b300-55aa51265d28"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"毛細血管","subitem_subject_scheme":"Other"},{"subitem_subject":"生体組織工学","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒドロゲル","subitem_subject_scheme":"Other"},{"subitem_subject":"ファイバー","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"生体と類似の毛細血管網および再生医療用重厚三次元臓器創製技術の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"生体と類似の毛細血管網および再生医療用重厚三次元臓器創製技術の開発"}]},"item_type_id":"8","owner":"3","path":["79"],"pubdate":{"attribute_name":"公開日","attribute_value":"2013-10-01"},"publish_date":"2013-10-01","publish_status":"0","recid":"11590","relation_version_is_last":true,"title":["生体と類似の毛細血管網および再生医療用重厚三次元臓器創製技術の開発"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-12-25T07:15:40.566722+00:00"}