{"created":"2023-07-25T08:11:28.242361+00:00","id":11668,"links":{},"metadata":{"_buckets":{"deposit":"5e7ec3ae-b3ab-42f8-8b7a-589263dd0c24"},"_deposit":{"created_by":18,"id":"11668","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"11668"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00011668","sets":["228:230:5171","57:58:59"]},"author_link":["55940","120380","6018","120381","120382","120383","120384"],"item_7_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-05-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"18","bibliographicPageStart":"9","bibliographicVolumeNumber":"65","bibliographic_titles":[{"bibliographic_title":"鹿児島大学医学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Medical journal of Kagoshima University","bibliographic_titleLang":"en"}]}]},"item_7_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2013-05-10","subitem_date_issued_type":"Issued"}]},"item_7_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Purpose: To examine the relationships between degrees of 99mTc pertechnetate (99mTcO4−) uptake after acid stimulation\nand the tumor size as well as histopathological subtypes of Warthin tumor and to evaluate the diagnostic accuracy of\n99mTcO4− scintigraphy and routine magnetic resonance (MR) imaging in differentiating Warthin and non-Warthin tumors of\nthe parotid gland. Methods: We reviewed a total of 83 pathologically proven parotid gland tumors in 79 patients (37 Warthin tumors and 46 non-Warthin tumors) that had been resected after 99mTcO4− scintigraphy with acid stimulation. Of these, MR imaging was performed in 53 patients before surgery (21 Warthin tumors and 33 non-Warthin tumors), among which contrastenhanced dynamic MR imaging was also performed in 50 patients (20 Warthin tumors and 30 non-Warthin tumors). The Kruskal–Wallis test was used to compare visually scored degrees of 99mTcO4 − uptake with tumor size and histopathological subtypes (epithelial components of 70%–80%, 40%–60%, and 20%–30%) in 37 Warthin tumors. The findings of T2-weighted and contrast-enhanced dynamic MR imaging were evaluated for the differential diagnosis of Warthin and non-Warthin\ntumors. We used the proportional test to compare the accuracy of 99mTcO4 − scintigraphy, T2-weighted MR imaging, and\ncontrast-enhanced dynamic MR imaging in diagnosing Warthin tumor. Results: 99mTcO4 − uptake in Warthin tumors showed marginal but statistically insignificant associations with tumor size (P = 0.092) and tumor pathological subtype (P = 0.070). Of the 8 false-negative tumors, 6 contained 1 or more of the following\nchanges: hemorrhage, hyaline or cystic degeneration, fibrosis, and infarction. A metastatic atypical meningioma showed\nfalse-positive uptake. The diagnostic accuracy was 89% for scintigraphy (sensitivity, 78%; specificity, 98%), 81% for T2- weighted MR imaging (sensitivity, 81%; specificity, 82%), and 82% for contrast-enhanced dynamic MR imaging (sensitivity,\n60%; specificity, 97%); significant differences in the diagnostic accuracy among the modalities were absent (P = 0.37).\nConclusions: 99mTcO4− uptake in Warthin tumors does not appear to depend solely on the tumor size or histological subtype and may be affected by nonviable parenchymal changes in the tumors. Scintigraphy may be equal to T2-weighted and contrast-enhanced dynamic MR imaging in differentiating Warthin and non-Warthin tumors.","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"目的：99mTc pertechnetateによる酸負荷唾液腺シンチグラフィ検査での集積程度がワルチン腫瘍の大きさや組織学的亜型と関連があるかを調べ，更に耳下腺のワルチン腫瘍と非ワルチン腫瘍の鑑別について，酸負荷唾液腺シンチグラフィとMRI検査の診断能を比較した。\n方法：酸負荷唾液腺シンチグラフィと手術が行われた79名の患者（ワルチン腫瘍37個，非ワルチン腫瘍46個）について後顧的にシンチグラフィの集積程度を視覚的に評価した。これらのうち53名が術前にMRI検査を受けており（ワルチン\n腫瘍21個，非ワルチン腫瘍33個），ダイナミック造影が50名（ワルチン腫瘍20個，非ワルチン腫瘍30個）になされていた。\nワルチン腫瘍の大きさや組織学的亜型（上皮成分の割合70－80%，40－60%，20－30%）と酸負荷唾液腺シンチグラフィの集積程度との関連を調べた。次にワルチン腫瘍か非ワルチン腫瘍かの診断能について，MRIのT2強調像とダイナミック造影像の所見を評価した。また，ワルチン腫瘍の診断における酸負荷唾液腺シンチグラフィとMRIのT2強調像とダ\nイナミック造影像について，正診率を統計学的に比較した。\n結果：ワルチン腫瘍における腫瘍の大きさや組織学的亜型と酸負荷唾液腺シンチグラフィでの集積程度との間にはいず\nれにおいても統計学的な有意差は得られなかった（P=0.092，P=0.070）。８例の偽陰性例の中には６例が出血や硝子化，嚢胞変性，線維化，梗塞といった何らかの変性を伴っていた。異型性髄膜腫の転移の１例が偽陽性であった。それぞれの正診率については酸負荷唾液腺シンチグラフィが89%（感度78%，特異度98%），MRIのT2強調像が81%（感度81%，特異度82%），MRIのダイナミック像が82%（感度60%，特異度97%）であり，これらの検査間での診断能に統計学的な有意差は得られなかった（P=0.37）。\n結論：ワルチン腫瘍における酸負荷唾液腺シンチグラフィでの集積は腫瘍の大きさや組織学的亜型のみが関与するわけ\nではなく，出血や腫瘍の非活動性的な実質の変性によっても影響される可能性が考えられた。酸負荷唾液腺シンチグラ\nフィにおけるワルチン腫瘍と非ワルチン腫瘍の診断能はMRIでのT2強調像やダイナミック造影検査とほぼ同等であっ\nた。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_7_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03685063","subitem_source_identifier_type":"PISSN"}]},"item_7_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00040104","subitem_source_identifier_type":"NCID"}]},"item_7_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_7_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"神宮司, メグミ","creatorNameLang":"ja"},{"creatorName":"JINGUJI, Megumi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"55940","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000070418862","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"田邉, 博昭","creatorNameLang":"ja"},{"creatorName":"TANABE, Hiroaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120380","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"中條, 政敬","creatorNameLang":"ja"},{"creatorName":"NAKAJO, Masataka","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"6018","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000020041379","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]},{"creatorNames":[{"creatorName":"中別府, 良昭","creatorNameLang":"ja"},{"creatorName":"NAKABEPPU, Yoshiaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120381","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"福倉, 良彦","creatorNameLang":"ja"},{"creatorName":"FUKUKURA, Yoshihiko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120382","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"松根, 彰志","creatorNameLang":"ja"},{"creatorName":"MATSUNE, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120383","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"義岡, 孝子","creatorNameLang":"ja"},{"creatorName":"YOSHIOKA, Takako","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"120384","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"p9-18 _鹿児島大学医学雑誌第65巻第1号.pdf","filesize":[{"value":"634.8 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"p9-18 _鹿児島大学医学雑誌第65巻第1号.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/11668/files/p9-18 _鹿児島大学医学雑誌第65巻第1号.pdf"},"version_id":"9062c11e-7744-4900-8971-efb628349415"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"parotid tumor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Warthin tumor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"99mTcO4− scintigraphy","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"magnetic resonance imaging","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"99mTc Pertechnetate Scintigraphy for Warthin Tumors of the Parotid Gland: Comparison of Histopathological and Magnetic Resonance Imaging findings","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"99mTc Pertechnetate Scintigraphy for Warthin Tumors of the Parotid Gland: Comparison of Histopathological and Magnetic Resonance Imaging findings","subitem_title_language":"en"},{"subitem_title":"ワルチン腫瘍の診断における酸負荷唾液腺シンチグラフィの集積とMRI 所見や病理組織所見との比較","subitem_title_language":"ja"}]},"item_type_id":"7","owner":"18","path":["59","5171"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-06-06"},"publish_date":"2014-06-06","publish_status":"0","recid":"11668","relation_version_is_last":true,"title":["99mTc Pertechnetate Scintigraphy for Warthin Tumors of the Parotid Gland: Comparison of Histopathological and Magnetic Resonance Imaging findings"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-05-27T05:39:37.250027+00:00"}