{"created":"2023-07-25T08:12:48.751449+00:00","id":13246,"links":{},"metadata":{"_buckets":{"deposit":"a7e8dfb4-d30b-4fc5-b959-464107ee2f27"},"_deposit":{"created_by":3,"id":"13246","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"13246"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00013246","sets":[]},"author_link":["118131","118130","6517"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Localization and regulation in reactive sites of DAMPs/PAMPs. Role of ATP from the activated plateles"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"DAMPs/PAMPs オウトウ ノ“バ ト テキセツカ” : カッセイカ ケッショウバン ノ ヤクワリ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2014-06-19"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2011-2013年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書　課題番号：25670764　研究代表者：丸山征郎（鹿児島大学・医歯（薬）学総合研究科・特任教授）","subitem_description_type":"Other"},{"subitem_description":"PAMPs、DAMPs双方のシグナル入力で一挙に炎症が惹起される。この時にはNF-kB活性化とインフラマソームの活性化がシンクロナイズされる。PAMPsの代表としてLPSを、DAMPsの代表として、HMGB1、あるいはATPを選び、同時に刺激すると、一挙にIL-1b (beta)、IL-18が産生された。in vivoでは炎症巣が形成された。血小板は代表的ATPソースであるが、インフラマソームアッセンブライも存在する。このインフラマソームを阻害すると、血小板凝集も阻害された。このように血小板はATPソースとしてばかりでなく、インフラマソームも配給することで、炎症巣を形成するものと考えられた。","subitem_description_type":"Other"},{"subitem_description":"This study examined infants' ability to perceive artificially produced three-dimensional object. In order to control shapes of three-dimensional objects, we created three-dimensional face and non-face objects (shoes) that contained no texture. First, behavioral study investigated infants' ability to learn the faces and non-face objects. Results were compared between categories and those showed the infants' ability to learn faces differs from their ability to learn non-face objects. Next, behavioral and brain activity measurement studies investigated effect of eye gaze direction of the faces. Results showed that infants could learn three-dimensional face by 8 months of age only in direct gaze. This suggested that gaze direction may affect three-dimensional face learning in infants","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"マルヤマ, イクロウ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"MARUYAMA, Ikuro"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"25670764"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"丸山, 征郎"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"25670764_丸山征郎.pdf","filesize":[{"value":"81.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"25670764_丸山征郎.pdf","url":"https://ir.kagoshima-u.ac.jp/record/13246/files/25670764_丸山征郎.pdf"},"version_id":"442fe90f-e2b5-406c-93a6-3e1c36a65380"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ATP","subitem_subject_scheme":"Other"},{"subitem_subject":"DAMP","subitem_subject_scheme":"Other"},{"subitem_subject":"PAMP","subitem_subject_scheme":"Other"},{"subitem_subject":"platelet","subitem_subject_scheme":"Other"},{"subitem_subject":"inflammation","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"DAMPs/PAMPs応答の“場と適切化” : 活性化血小板の役割","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"DAMPs/PAMPs応答の“場と適切化” : 活性化血小板の役割"}]},"item_type_id":"8","owner":"3","path":["80"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-05-20"},"publish_date":"2015-05-20","publish_status":"0","recid":"13246","relation_version_is_last":true,"title":["DAMPs/PAMPs応答の“場と適切化” : 活性化血小板の役割"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-12-25T07:18:54.308118+00:00"}