{"created":"2023-07-25T08:12:48.796858+00:00","id":13247,"links":{},"metadata":{"_buckets":{"deposit":"9fec6fde-b186-4844-b0ac-007d572416c7"},"_deposit":{"created_by":18,"id":"13247","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"13247"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00013247","sets":["57:80"]},"author_link":["118132"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2014-06-19","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2011-2013年度科学研究費助成事業（挑戦的萌芽研究）研究成果報告書　課題番号：24659159　研究代表者：\n小戝健一郎（鹿児島大学・医歯（薬）学総合研究科・教授）","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"ヒトES細胞、iPS細胞を用いた再生医療技術の臨床応用において、混在した未分化細胞から生じる腫瘍の克服は、重要な課題である。研究者が癌治療用に独自開発したm-CRA（多因子で精密に癌特異化する増殖制御型アデノウイルスベクター）技術を用いて、この問題をある程度解決できることを示唆する科学的成果を得た。科学的にも独創的な研究であり、先端医療実現を進めるという点でも意義ある成果と思われる。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"The tumor that is derived from the contaminated undifferentiated-cells is the major obstacle to the clinical application of human ES and/or iPS cell-based regenerative medicine. Here we developed a novel methodology that might conquer this obstacle to some degrees using m-CRA (conditionally replicating adenovirus with multiple tumor-specific factors), which we had initially developed for treating cancer. This methodology is not only a scientifically novel and original but also meaningful in terms of facilitating clinical development of these sorts of innovative therapy.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"24659159"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小戝, 健一郎","creatorNameLang":"ja"},{"creatorName":"KOSAI, Kenichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"118132","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-31"}],"displaytype":"detail","filename":"23659159_小戝健一郎.pdf","filesize":[{"value":"246.4 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"23659159_小戝健一郎.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/13247/files/23659159_小戝健一郎.pdf"},"version_id":"190c81fa-34f5-4d3b-aa25-5382ec1c6e0b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"再生医学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発","subitem_title_language":"ja"},{"subitem_title":"Development of conditionally replicating adenovirus that treats human ES/iPS-derived tumor","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["80"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-05-21"},"publish_date":"2015-05-21","publish_status":"0","recid":"13247","relation_version_is_last":true,"title":["ヒトES/iPS細胞由来の腫瘍を標的治療する増殖型アデノウイルス技術の開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-05-24T00:24:57.856176+00:00"}