{"created":"2023-07-25T08:13:32.705124+00:00","id":14428,"links":{},"metadata":{"_buckets":{"deposit":"9b9ea6ff-952a-4997-b016-cccfaf190ef8"},"_deposit":{"created_by":18,"id":"14428","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"14428"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00014428","sets":["57:86"]},"author_link":["132103"],"item_5_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1086","bibliographicVolumeNumber":"91","bibliographic_titles":[{"bibliographic_title":"British Journal of Radiology","bibliographic_titleLang":"en"}]}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2018-09-19"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Objective: To identify risk factors for symptomatic radiation pneumonitis (RP) after stereotactic radiation therapy (SRT) for lung tumours.\nMethods: We retrospectively evaluated 68 lung tumours in 63 patients treated with SRT between 2011 and 2015. RP was graded according to the National Cancer Institute—Common Terminology Criteria for Adverse Events version 4.0. SRT was delivered at 7.0–12.0 Gy per each fraction, once daily, to a total of 48–64 Gy (median, 50 Gy). Univariate analysis was performed to assess patient- and treatment-related factors, including age, sex, smoking index (SI), pulmonary function, tumour location, serum Krebs von den Lungen-6 value (KL-6), dose-volume metrics (V5, V10, V20, V30, V40 and VS5), homogeneity index of the planning target volume (PTV), PTV dose, mean lung dose (MLD), contralateral MLD and V2, PTV volume, lung volume and the PTV/lung volume ratio (PTV/Lung). Performance of PTV/Lung in predicting symptomatic RP was also analysed using receiver operating characteristic (ROC) analysis.\nResults: The median follow-up period was 21 months. 10 of 63 patients (15.9%) developed symptomatic RP after SRT. On univariate analysis, V10, V20, PTV volume and PTV/Lung were significantly associated with occurrence of RP ≥Grade 2. ROC curves indicated that symptomatic RP could be predicted using PTV/Lung [area under curve (AUC): 0.88, confidence interval (CI: 0.78–0.95), cut-off value: 1.09, sensitivity: 90.0% and specificity: 72.4%].\nConclusion: PTV/Lung is a good predictor of symptomatic RP after SRT.\nAdvances in knowledge: The cases with high PTV/Lung should be carefully monitored with caution for the occurrence of RP after SRT.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第476号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"British Institute of Radiology","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1259/bjr.20170453","subitem_relation_type_select":"DOI"}}]},"item_5_relation_13":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"British Institute of Radiology"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.birpublications.org/","subitem_relation_type_select":"URI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2018 The Authors. Published by the British Institute of Radiology","subitem_rights_language":"en"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"492","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員 : 吉浦敬】 "}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2018-06-06"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"上山, 友子","creatorNameLang":"ja"},{"creatorName":"ウエヤマ, トモコ","creatorNameLang":"ja-Kana"},{"creatorName":"Ueyama, Tomoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"132103","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-09-30"}],"displaytype":"detail","filename":"Diss_上山_友子_ISK476_2018.pdf","filesize":[{"value":"393.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Diss_上山_友子_ISK476_2018","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/14428/files/Diss_上山_友子_ISK476_2018.pdf"},"version_id":"8b59bd02-1157-4c22-8c01-4947702523ea"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-10-23"}],"displaytype":"detail","filename":"Abstract_上山_友子_4510810293_2018.pdf","filesize":[{"value":"193.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_上山_友子_4510810293_2018","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/14428/files/Abstract_上山_友子_4510810293_2018.pdf"},"version_id":"d4fd11cd-1020-4e23-b941-e9ea86641fd1"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-09-26"}],"displaytype":"detail","filename":"Result_Ueyama_Tomoko_isk_476_208.pdf","filesize":[{"value":"810.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Ueyama_Tomoko_isk_476_208","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14428/files/Result_Ueyama_Tomoko_isk_476_208.pdf"},"version_id":"3bacb07c-cbc5-4b20-b7f7-f715991677f2"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-09-26"}],"displaytype":"detail","filename":"Comments_Ueyama_Tomoko_isk_476_2018.pdf","filesize":[{"value":"401.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Ueyama_Tomoko_isk_476_2018","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14428/files/Comments_Ueyama_Tomoko_isk_476_2018.pdf"},"version_id":"d5a3280a-2d30-4138-ab4f-6f24409c5e66"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours : clinical usefulness of the planning target volume to total lung volume ratio","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours : clinical usefulness of the planning target volume to total lung volume ratio","subitem_title_language":"en"},{"subitem_title":"肺腫瘍に対する定位放射線治療における放射線肺炎のリスク因子に関する研究 : 肺体積に占める計画標的体積の割合の臨床的有用性","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-09-26"},"publish_date":"2018-09-26","publish_status":"0","recid":"14428","relation_version_is_last":true,"title":["Risk factors for radiation pneumonitis after stereotactic radiation therapy for lung tumours : clinical usefulness of the planning target volume to total lung volume ratio"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:48:11.176417+00:00"}