{"created":"2023-07-25T08:13:44.488277+00:00","id":14635,"links":{},"metadata":{"_buckets":{"deposit":"cd4633a9-e3a2-4ad0-a618-859950ad86ba"},"_deposit":{"created_by":18,"id":"14635","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"14635"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00014635","sets":["57:86"]},"author_link":["133106"],"item_5_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"537","bibliographicPageStart":"529","bibliographicVolumeNumber":"35","bibliographic_titles":[{"bibliographic_title":"Pediatric Surgery International","bibliographic_titleLang":"en"}]}]},"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-03-07","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2019-03-25"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学 "}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Purpose: Portal hypertension in patients with biliary atresia (BA) is generally thought to result from portal vein (PV) narrowing secondary to hepatic fibrosis. To test the hypothesis, we morphometrically analyzed the PVs and hepatic arteries (HAs).\nMethods: Morphometrical analyses of 25 BA and 26 non-BA liver biopsy specimens from patients treated from 2000 to 2014. The total specimen area, the fibrotic portal area, vessel diameter and medial thickness of the HAs were measured.\nResults: The PV diameter in BA patients was significantly smaller than that in non-BA patients. In BA, the numbers of normal-sized PVs and capillaries were decreased and increased, respectively. The PV diameter was not significantly correlated with the degree of fibrosis. We newly found that medial hypertrophy and the HA diameter increased with the number of endothelial cells in BA. The PV diameter was not significantly correlated with the medial thickness and was positively correlated with the HA diameter in BA.\nConclusions: The narrowing of the PV is unlikely to occur secondarily to liver fibrosis. The medial hypertrophy of the HA is not correlated with the decrease in the PV blood flow. These findings seem to be unique to the primary vascular lesions of BA.\n\n\nRyuta Masuya, Toshihiro Muraji, Haruo Ohtani, Motoi Mukai, Shun Onishi, Toshio Harumatsu, Koji Yamada, Waka Yamada, Takafumi Kawano, Seiro Machigashira, Kazuhiko Nakame, Tatsuru Kaji & Satoshi Ieiri\nMorphometric demonstration of portal vein stenosis and hepatic arterial medial hypertrophy in patients with biliary atresia\nPediatric Surgery International(2019), 35, 529–537\nThis is a post-peer-review, pre-copyedit version of an article published in Pediatric Surgery International.\nThe final authenticated version is available online at:\nhttps://doi.org/10.1007/s00383-019-04459-4.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第500号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Springer","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"494","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員:家入里志】 "}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2019-02-06"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"桝屋, 隆太","creatorNameLang":"ja"},{"creatorName":"マスヤ, リュウタ","creatorNameLang":"ja-Kana"},{"creatorName":"Masuya, Ryuta","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"133106","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-18"}],"displaytype":"detail","filename":"Diss_桝屋_隆太_ISK500_2018（著者最終稿）.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Diss_桝屋_隆太_ISK500_2018","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/14635/files/Diss_桝屋_隆太_ISK500_2018（著者最終稿）.pdf"},"version_id":"fc379586-2149-407f-be31-e5da7aeb1b6c"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-17"}],"displaytype":"detail","filename":"Abstract_桝屋_隆太_4515800128_2018.pdf","filesize":[{"value":"356.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_桝屋_隆太_4515800128_2018","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/14635/files/Abstract_桝屋_隆太_4515800128_2018.pdf"},"version_id":"6c00ab74-f173-40dc-9494-ebfafb160c9e"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-22"}],"displaytype":"detail","filename":"Result_Masaya_Ryuta_isk_500.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Masaya_Ryuta_isk_500","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14635/files/Result_Masaya_Ryuta_isk_500.pdf"},"version_id":"687387d6-2aa9-4ffc-ab0a-3577b51e4761"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-04-22"}],"displaytype":"detail","filename":"Comments_Masuya_Ryuta_isk_500.pdf","filesize":[{"value":"568.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Masuya_Ryuta_isk_500","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14635/files/Comments_Masuya_Ryuta_isk_500.pdf"},"version_id":"36c04e5c-c3b2-4979-bbcf-9ba36a688aeb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Biliary atresia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Portal vein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Hepatic artery","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Morphometrical analysis","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Morphometric demonstration of portal vein stenosis and hepatic arterial medial hypertrophy in patients with biliary atresia.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Morphometric demonstration of portal vein stenosis and hepatic arterial medial hypertrophy in patients with biliary atresia.","subitem_title_language":"en"},{"subitem_title":"胆道閉鎖症の肝生検検体における門脈および肝動脈の形態計測学的検討","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-04-17"},"publish_date":"2019-04-17","publish_status":"0","recid":"14635","relation_version_is_last":true,"title":["Morphometric demonstration of portal vein stenosis and hepatic arterial medial hypertrophy in patients with biliary atresia."],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:49:37.862129+00:00"}