{"created":"2023-07-25T08:13:58.965010+00:00","id":14900,"links":{},"metadata":{"_buckets":{"deposit":"f1e79887-cfcb-44c7-ac75-cfcd54640e90"},"_deposit":{"created_by":18,"id":"14900","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"14900"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00014900","sets":["57:86"]},"author_link":["134505"],"item_5_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1285","bibliographicPageStart":"1278","bibliographicVolumeNumber":"83","bibliographic_titles":[{"bibliographic_title":"Circulation Journal","bibliographic_titleLang":"en"}]}]},"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2019-09-06","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2019-09-17"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Background: This study was designed to investigate the relationship between right ventricular wall stress (RVWS) and plasma B-type natriuretic peptide (BNP) levels in patients with pulmonary hypertension (PH).\nMethods and Results: The 57 consecutive PH patients and 8 control subjects were enrolled. Right heart catheterization (RHC), echocardiography, and BNP measurements were performed, and RVWS and left ventricular wall stress (LVWS) were calculated with the formula based on Laplace's law. Systolic RVWS and end-diastolic RVWS were higher in PH patients compared with controls (systolic RVWS: 77±41 vs. 17±5 kdynes/cm2 (P<0.0001), end-diastolic RVWS: 15±12 vs. 8±2 kdynes/cm2 (P<0.0005)). Univariate analyses showed that logBNP at baseline correlated with systolic RVWS (r=0.58, P<0.0001) and end-diastolic RVWS (r=0.61, P<0.0001). We performed multivariate regression analysis and determined that end-diastolic RVWS was an independent determinant of logBNP in patients with PH. In addition, change in plasma BNP levels after treatment correlated with change in systolic RVWS (r=0.70, P<0.0001) and change in end-diastolic RVWS (r=0.68, P<0.0001).\nConclusions: Both systolic and end-diastolic RVWS were elevated in patients with PH, and correlated with the symptoms of PH. End-diastolic RVWS was an independent determinant of plasma BNP levels in PH patients.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第518号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Circulation Society","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1253/circj.CJ-18-1155","subitem_relation_type_select":"DOI"}}]},"item_5_relation_13":{"attribute_name":"情報源","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"Circulation Journal"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://www.jstage.jst.go.jp/browse/circj/-char/en","subitem_relation_type_select":"URI"}}]},"item_5_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"All rights are reserved to the Japanese Circulation Society.","subitem_rights_language":"en"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員:大石充】"}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2019-05-08"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"内山, 奈美","creatorNameLang":"ja"},{"creatorName":"ウチヤマ, ナミ","creatorNameLang":"ja-Kana"},{"creatorName":"Uchiyama, Nami","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-12-20"}],"displaytype":"detail","filename":"Diss_内山_奈美_ISK518_2019.pdf","filesize":[{"value":"971.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Diss_内山_奈美_ISK518_2019","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/14900/files/Diss_内山_奈美_ISK518_2019.pdf"},"version_id":"d332a240-cecc-4a6a-89cd-949073951980"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-12-20"}],"displaytype":"detail","filename":"Abstract_内山_奈美_4509810165_2019.pdf","filesize":[{"value":"72.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_内山_奈美_4509810165_2019","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/14900/files/Abstract_内山_奈美_4509810165_2019.pdf"},"version_id":"8adf2cf0-9cc2-49dd-9ca2-c9ddbb0999a7"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-08"}],"displaytype":"detail","filename":"Result_Uchiyama_Nami_isk_518.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Uchiyama_Nami_isk_518","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14900/files/Result_Uchiyama_Nami_isk_518.pdf"},"version_id":"e32600c8-2158-4f40-bf0a-fab6d20b37d3"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-10-08"}],"displaytype":"detail","filename":"Comments_Uchiyama_Nami_isk_518.pdf","filesize":[{"value":"458.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Uchiyama_Nami_isk_518","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14900/files/Comments_Uchiyama_Nami_isk_518.pdf"},"version_id":"70855ee5-1225-4e66-ab67-982108b73e8f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"B-type natriuretic peptide","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Pulmonary hypertension","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Right ventricular wall stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Correlation of Right Ventricular Wall Stress with Plasma B-Type Natriuretic Peptide Levels in Patients with Pulmonary Hypertension","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Correlation of Right Ventricular Wall Stress with Plasma B-Type Natriuretic Peptide Levels in Patients with Pulmonary Hypertension","subitem_title_language":"en"},{"subitem_title":"肺高血圧症における右室壁応力と血漿BNP値の相関","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-10-08"},"publish_date":"2019-10-08","publish_status":"0","recid":"14900","relation_version_is_last":true,"title":["Correlation of Right Ventricular Wall Stress with Plasma B-Type Natriuretic Peptide Levels in Patients with Pulmonary Hypertension"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:50:38.436399+00:00"}