{"created":"2023-07-25T08:14:03.176842+00:00","id":14994,"links":{},"metadata":{"_buckets":{"deposit":"164d63a4-e339-4983-8dd0-4c21cf6404eb"},"_deposit":{"created_by":18,"id":"14994","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"14994"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00014994","sets":["57:86"]},"author_link":["134822"],"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-01-14","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2019-10-02"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Objective: The main purpose was to clarify the optimal D-dimer cutoff level during pregnancy to exclude deep vein thrombosis (DVT) prior to Cesarean section. The secondary purpose was to determine whether D-dimer can predict severe postpartum hemorrhage (PPH) in Cesarean section patients.\nMethods: Two hundred and seventy eight elective Cesarean section cases were enrolled. Clinical factors and blood parameters at 34-37 weeks of gestation were analyzed. To detect DVT, lower extremities veins were examined using color Doppler ultrasonography in cases with D-dimer level ＞＿ 1.5 μg/mL. In addition, postpartum blood loss amounts\nduring Cesarean section were recorded.\nResults: Five DVT cases occurred in 250 singleton pregnancies, and 2 DVT cases occurred in 28 twin pregnancies. The overall incidence of DVT was 2.5%. The D-dimer level was higher in DVT cases than in non-DVT cases (3.84±1.97 vs. 2.31±1.48 μg/mL, P<0.01). The optimal D-dimer cutoff level was 2.6 μg/mL with a negative predictive value of 99.5%, and sensitivity of 85.7%. PPH during Cesarean section was positively correlated with D-dimer level in all pregnancies. However, this relationship disappeared after excluding twin pregnancies.\nConclusion: A D-dimer level < 2.6 μg/mL at 34-37 weeks of gestation has the potential to exclude DVT. D-dimer can be an independent predictor for severe PPH for all Cesarean section cases, including twin pregnancies.\n\nYUJI ORITA, TOMONORI HAMADA, SHINICHI TOGAMI, TSUTOMU DOUCHI, HIROAKI KOBAYASHI\nThe Optimal Cutoff Level of D-Dimer during Pregnancy to Exclude Deep Vein Thrombosis, and the Association between D-Dimer and Postpartum Hemorrhage in Cesarean Section Patients\nThe Kurume Medical Journal (2019) 66(2) 107-114\nhttps://doi.org/10.2739/kurumemedj.MS662003","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第533号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Kurume University School of Medicine","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員:小林裕明】 "}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2019-10-02"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"折田, 有史","creatorNameLang":"ja"},{"creatorName":"オリタ, ユウジ","creatorNameLang":"ja-Kana"},{"creatorName":"Orita, Yuji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"134822","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-08-05"}],"displaytype":"detail","filename":"Diss_折田_有史_ISK533_2019.pdf","filesize":[{"value":"781.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Diss_折田_有史_ISK533_2019","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/14994/files/Diss_折田_有史_ISK533_2019.pdf"},"version_id":"6951a2a3-ac54-4bb9-b2a1-c1bf9317d80a"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-03"}],"displaytype":"detail","filename":"Abstract_折田_有史_4512800161_2019.pdf","filesize":[{"value":"146.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_折田_有史_4512800161_2019","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/14994/files/Abstract_折田_有史_4512800161_2019.pdf"},"version_id":"894971c9-c686-4262-977a-48f8aa2699cf"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-13"}],"displaytype":"detail","filename":"Result_Orita_Yuji_isk_533.pdf","filesize":[{"value":"508.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Orita_Yuji_isk_533","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14994/files/Result_Orita_Yuji_isk_533.pdf"},"version_id":"55340925-43e2-4e74-a911-8f895013a0c8"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-03-13"}],"displaytype":"detail","filename":"Comments_Orita_Yuji_isk_533.pdf","filesize":[{"value":"233.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Orita_Yuji_isk_533","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/14994/files/Comments_Orita_Yuji_isk_533.pdf"},"version_id":"fa817e3b-0f2d-4648-b88f-9915bf856812"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"D-dimer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"deep vein thrombosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cutoff level","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"singleton","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"twin pregnancies","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"postpartum hemorrhage","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"The optimal cutoff level of D-dimer during pregnancy to exclude deep vein thrombosis, and the association between D-dimer and postpartum hemorrhage in Cesarean section patients","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The optimal cutoff level of D-dimer during pregnancy to exclude deep vein thrombosis, and the association between D-dimer and postpartum hemorrhage in Cesarean section patients","subitem_title_language":"en"},{"subitem_title":"帝王切開術前の深部静脈血栓症に対するD-dimerのカットオフ値およびD-dimerと帝王切開術中出血量の関与についての検討","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-03-13"},"publish_date":"2020-03-13","publish_status":"0","recid":"14994","relation_version_is_last":true,"title":["The optimal cutoff level of D-dimer during pregnancy to exclude deep vein thrombosis, and the association between D-dimer and postpartum hemorrhage in Cesarean section patients"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:51:27.280001+00:00"}