{"created":"2023-07-25T08:14:11.462227+00:00","id":15168,"links":{},"metadata":{"_buckets":{"deposit":"025ada26-c53b-495d-89e7-57a80b5b49aa"},"_deposit":{"created_by":18,"id":"15168","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"15168"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00015168","sets":["57:86"]},"author_link":["135798"],"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-03-06","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2020-03-12"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Although postoperative management of gastric cancer is determined by pathological stage based on the tumor-node-metastasis classification, predicting disease recurrence and prognosis in patients undergoing gastrectomy is clinically difficult. We investigated the depth of tumor invasion and tumor size in resected specimens from patients with gastric cancer and assessed the clinical utility of primary tumor score (PTS) calculated by tumor depth and size as a prognostic marker. We classified 247 patients with gastric cancer into three groups based on cut-off values for deeper tumor invasion (pT2–T4) and larger tumor size (≥ 45 mm) as a PTS of 2 (both abnormalities), 1 (one abnormality), or 0 (neither abnormality). PTS correlated significantly with lymph node metastasis, lymphovascular invasion, and stage (P < 0.0001 each). Survival differences among groups based on PTS were significant (P < 0.0001). Multivariate analysis identified PTS alone as an independent prognostic factor (P = 0.0363). PTS derived from primary tumor information alone is a potentially useful marker for predicting tumor progression and prognosis in postoperative patients with gastric cancer.\n\nNaoto Haraguchi, Takaaki Arigami, Yoshikazu Uenosono, Shigehiro Yanagita, Yasuto Uchikado, Shinichiro Mori, Hiroshi Kurahara, Yuko Kijima, Akihiro Nakajo, Kosei Maemura, Sumiya Ishigami and Shoji Natsugoe\nClinical significance of primary tumor score determined by tumor depth and size in patients with resectable gastric cancer\nOncotarget. 2018; 9:8512-8520\nhttps://doi.org/10.18632/oncotarget.23953","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第538号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Oncotarget","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員:夏越祥次】"}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2019-11-16"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"原口, 尚士","creatorNameLang":"ja"},{"creatorName":"ハラグチ, ナオト","creatorNameLang":"ja-Kana"},{"creatorName":"Haraguchi, Naoto","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"135798","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-01"}],"displaytype":"detail","filename":"Diss_原口_尚士_ISK538_2019.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_6","mimetype":"application/pdf","url":{"label":"Diss_原口_尚士_ISK538_2019","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/15168/files/Diss_原口_尚士_ISK538_2019.pdf"},"version_id":"bd563153-e25d-48b0-b794-84ca773ac382"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-01"}],"displaytype":"detail","filename":"Abstract_原口_尚士_4509810343_2019.pdf","filesize":[{"value":"121.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_原口_尚士_4509810343_2019","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/15168/files/Abstract_原口_尚士_4509810343_2019.pdf"},"version_id":"6e745a68-f907-4aaf-bbaa-542367e7d604"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-21"}],"displaytype":"detail","filename":"Result_Haraguchi_Naoto_isk_538.pdf","filesize":[{"value":"376.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Haraguchi_Naoto_isk_538","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15168/files/Result_Haraguchi_Naoto_isk_538.pdf"},"version_id":"e72258de-67d8-400b-acdf-c3d50f4c4354"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-21"}],"displaytype":"detail","filename":"Comments_Haraguchi_Naoto_isk_538.pdf","filesize":[{"value":"180.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Haraguchi_Naoto_isk_538","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15168/files/Comments_Haraguchi_Naoto_isk_538.pdf"},"version_id":"b041a035-60af-4503-bd7b-8b1691833809"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"primary tumor score","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"tumor size","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"depth of tumor invasion","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"prognostic factor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"gastric cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Clinical significance of primary tumor score determined by tumor depth and size in patients with resectable gastric cancer","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical significance of primary tumor score determined by tumor depth and size in patients with resectable gastric cancer","subitem_title_language":"en"},{"subitem_title":"切除可能な胃癌に対する深達度と腫瘍径から測定される Primary Tumor Scoreの臨床的意義","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-05-21"},"publish_date":"2020-05-21","publish_status":"0","recid":"15168","relation_version_is_last":true,"title":["Clinical significance of primary tumor score determined by tumor depth and size in patients with resectable gastric cancer"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:56:29.871231+00:00"}