{"created":"2023-07-25T08:14:11.899216+00:00","id":15178,"links":{},"metadata":{"_buckets":{"deposit":"b5a857f6-4dda-4aad-badd-fd363bf8183a"},"_deposit":{"created_by":29,"id":"15178","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"15178"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00015178","sets":["57:86"]},"author_link":["135828"],"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-03-06","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2020-03-25"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学 "}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Intima-media thickness (IMT), plaque score (PS) and brachial-ankle pulse wave velocity (baPWV) are non-invasive parameters for evaluation of atherosclerosis. There have been no reports investigating the associations between IMT, PS, or baPWV and known risk factors for atherosclerosis in the same participants. This study aimed to compare the contributed risk factors among IMT, PS, and baPWV.We enrolled 3,128 male participants who underwent health checkups. Carotid ultrasonography was used to measure IMT and PS, and baPWV was measured using an automatic device. We analyzed the association between these parameters and risk factors for atherosclerosis including obesity, smoking, alcohol, high blood pressure (BP), impaired fasting glucose (IFG), dyslipidemia (DL), and high-sensitivity C-reactive protein (hs-CRP).Multivariate logistic regression analysis revealed high IMT (>0.9 mm) to be independently associated with high BP. The presence of atherosclerosis (PS>1.1 mm) was independently associated with high BP, IFG, and DL. In addition, advanced atherosclerosis (PS>5.1 mm) showed a significant association with high BP, IFG, DL, log hs-CRP, and smoking. High baPWV (>1,600 cm/sec) was significantly correlated with high BP, IFG, and log hs-CRP. IMT, PS and baPWV are all associated with different risk factors among Japanese male participants. Only high BP was a common risk factor for all three parameters. Furthermore, hs-CRP was associated with advanced atherosclerosis, not but with the presence of atherosclerosis.\n\nSatoko Ojima, Takuro Kubozono, Shin Kawasoe, Takeko Kawabata, Masaaki Miyata, Hironori Miyahara, Shigeho Maenohara & Mitsuru Ohishi\nAssociation of risk factors for atherosclerosis, including high-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population\nHypertension Research volume 43, pages422–430 (2020)\nhttps://doi.org/10.1038/s41440-019-0388-2","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第548号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"【指導教員:大石充】"}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2020-01-08"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小島, 聡子","creatorNameLang":"ja"},{"creatorName":"オジマ, サトコ","creatorNameLang":"ja-Kana"},{"creatorName":"Ojima, Satoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"135828","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-02"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2020-03-06"}],"filename":"Diss_小島_聡子_ISK548_2019.pdf","filesize":[{"value":"584.5 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Diss_小島_聡子_ISK548_2019","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/15178/files/Diss_小島_聡子_ISK548_2019.pdf"},"version_id":"b5de8494-42e1-4aa5-a25a-967c951395ba"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-02"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2020-03-06"}],"filename":"Abstract_小島_聡子_4516810058_2019.pdf","filesize":[{"value":"82.8 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Abstract_小島_聡子_4516810058_2019","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/15178/files/Abstract_小島_聡子_4516810058_2019.pdf"},"version_id":"ae01191c-d826-4c16-a254-1523931dcd5a"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-21"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2020-03-06"}],"filename":"Result_Ojima_Satoko_isk_548.pdf","filesize":[{"value":"245.3 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Result_Ojima_Satoko_isk_548","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15178/files/Result_Ojima_Satoko_isk_548.pdf"},"version_id":"157a922e-e438-4795-9732-6239689e78f3"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-05-21"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2020-03-06"}],"filename":"Comments_Ojima_Satoko_isk_548.pdf","filesize":[{"value":"94.4 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Comments_Ojima_Satoko_isk_548","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15178/files/Comments_Ojima_Satoko_isk_548.pdf"},"version_id":"46136090-4a59-43c7-b3c2-aa1872f8ba5a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"intima-media thickness","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"plaque score","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"brachial-ankle pulse wave velocity","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high blood pressure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"high-sensitivity C-reactive protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population","subitem_title_language":"en"},{"subitem_title":"男性における高感度CRPを含めた動脈硬化の危険因子と頸動脈内膜中膜複合体厚,頸動脈プラークスコア及び上腕足首脈波伝播速度との関連","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"29","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-05-21"},"publish_date":"2020-05-21","publish_status":"0","recid":"15178","relation_version_is_last":true,"title":["Association of risk factors for atherosclerosis, including higb-sensitivity C-reactive protein, with carotid intima-media thickness, plaque score, and pulse wave velocity in a male population"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2025-08-28T05:34:35.921844+00:00"}