{"created":"2023-07-25T08:14:14.764551+00:00","id":15243,"links":{},"metadata":{"_buckets":{"deposit":"b84cad78-3479-44e4-95a3-13ebfffc1b18"},"_deposit":{"created_by":18,"id":"15243","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"15243"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00015243","sets":["57:86"]},"author_link":["136181"],"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2020-05-08","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2020-05-13"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(医学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Medical Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Background: Human T-cell lymphotropic virus type 1 (HTLV-1) is a retrovirus that causes adult T-cell leukemia/lymphoma (ATL), an aggressive form of T-cell malignancy. The relationship between HTLV-1 infection and cancer progression is controversial. HTLV-1 encodes oncogenic protein TAX1 and it is hypothesized that HTLV-1 infection is associated with breast cancer progression. In this study, we evaluated the relationship between HTLV-1 infection and clinicopathological factors in breast cancer patients. Methods: We retrospectively analyzed 610 patients with primary breast cancer who underwent surgical treatment without preoperative chemotherapy at Kagoshima University Hospital between January 2001 and January 2015. Results: When patients with and without HTLV-1 infection were compared, no differences in clinicopathological factors were observed, except for age. Disease-free survival and overall survival rates did not differ between groups. Conclusions: HTLV-1–positive patients were significantly older than HTLV-1–negative patients. It was supposed to be due to the fact that the HTLV-1 infection rate is decreasing. Any effect of HTLV-1 infection on breast cancer progression appears to be negligibly small.\n\nMunetsugu Hirata, Yoshiaki Shinden, Ayako Nagata, Yuki Nomoto, Hazuki Saho, Akihiro Nakajo, Takaaki Arigami, Hiroshi Kurahara, Kosei Maemura, Shoji Natsugoe, Yuko Kijima\nClinical Features of Breast Cancer Patients with Human T-Cell Lymphotropic Virus Type-1 Infection\nAsian Pacific Journal of Cancer Prevention, 20(6), 2019 P.1909-1912\nDOI:10.31557/APJCP.2019.20.6.1909","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲総研第563号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Asian Pacific Journal of Cancer Prevention","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"カゴシマ ダイガク","subitem_publisher_language":"ja-Kana"}]},"item_5_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"【指導教員:夏越祥次, 大塚隆生】"}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_value":"【学位申請日】2020-01-08"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"平田, 宗嗣","creatorNameLang":"ja"},{"creatorName":"ヒラタ, ムネツグ","creatorNameLang":"ja-Kana"},{"creatorName":"Hirata, Munetsugu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"136181","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-06"}],"displaytype":"detail","filename":"Diss_平田_宗嗣_ISK563_2020.pdf","filesize":[{"value":"328.5 kB"}],"format":"application/pdf","licensetype":"license_9","mimetype":"application/pdf","url":{"label":"Diss_平田_宗嗣_ISK563_2020","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/15243/files/Diss_平田_宗嗣_ISK563_2020.pdf"},"version_id":"8fab1bb6-a270-44e4-a7de-66e230de7677"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-05-06"}],"displaytype":"detail","filename":"Abstract_平田_宗嗣_4507810255_2019.pdf","filesize":[{"value":"125.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Abstract_平田_宗嗣_4507810255_2019","objectType":"abstract","url":"https://ir.kagoshima-u.ac.jp/record/15243/files/Abstract_平田_宗嗣_4507810255_2019.pdf"},"version_id":"3cc11b59-8c16-4bc9-a826-d1464a53c83f"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-19"}],"displaytype":"detail","filename":"Result_Hirata_Munetsugu_isk_563.pdf","filesize":[{"value":"879.6 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Result_Hirata_Munetsugu_isk_563","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15243/files/Result_Hirata_Munetsugu_isk_563.pdf"},"version_id":"be770c17-34cc-4e51-93a1-1f552cd4a025"},{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-19"}],"displaytype":"detail","filename":"Comments_Hirata_Munetsugu_isk_563.pdf","filesize":[{"value":"431.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Comments_Hirata_Munetsugu_isk_563","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/15243/files/Comments_Hirata_Munetsugu_isk_563.pdf"},"version_id":"0b6e06f4-af94-421c-8d52-d09aefc5358d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HTLV-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"breast cancer","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"clinicopathological factors","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Clinical Features of Breast Cancer Patients with Human T-Cell Lymphotropic Virus Type-1 Infection","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Clinical Features of Breast Cancer Patients with Human T-Cell Lymphotropic Virus Type-1 Infection","subitem_title_language":"en"},{"subitem_title":"乳癌患者におけるHTLV-1感染の臨床的意義","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"18","path":["86"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-08-19"},"publish_date":"2020-08-19","publish_status":"0","recid":"15243","relation_version_is_last":true,"title":["Clinical Features of Breast Cancer Patients with Human T-Cell Lymphotropic Virus Type-1 Infection"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-09T01:57:52.825380+00:00"}