{"created":"2023-07-25T08:03:38.054545+00:00","id":1633,"links":{},"metadata":{"_buckets":{"deposit":"3958f947-7e70-43e9-812e-c80b625511b5"},"_deposit":{"created_by":29,"id":"1633","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"1633"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00001633","sets":["228:274:4807","64:65"]},"author_link":[],"item_7_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-03-26","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"25","bibliographicPageStart":"19","bibliographicVolumeNumber":"28","bibliographic_titles":[{"bibliographic_title":"鹿児島大学歯学部紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Annals of Kagoshima University Dental School","bibliographic_titleLang":"en"}]}]},"item_7_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-03-26","subitem_date_issued_type":"Issued"}]},"item_7_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Here we describe effects of neuroactive peptides, vasopressin, vasopressin fragment, and its analog, NC-1900, on cognitive functions and CCh-induced amnesia. Vasopressin (AVB-s) and its fragments are synthesized in the central nervous, and it is well known to regulate diuretic action. However, vasopressin receptors are distributed not only in the supraoptic nucleus and the paraventricular nucleus but also throughout the central nervous system. This fact shows that an action ofAVB-> is not restricted to the anti- diuretic action, and it is suggested thatAVFVp and its metabolites regulate cognitive function such as learning and memory.   In order to determine the mechanism of action of a new AVPw analog, NC-1 900, on memory process, we investigated the facilitative effect ofNC-1900 on memory performance in eight-arm radial maze and in passive avoidance (PA) tasks in nonamnesic and amnesic mice. The improved effect ofNC-1900 on the CO-induced amnesia was caused by VIA receptor but not V2, and the effect of NC-1900 on memory retention test performance appeared to be due to activation of the protein kinase C (PKC) signaling pathway via VIA receptors.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_7_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03897834","subitem_source_identifier_type":"PISSN"}]},"item_7_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN0035442X","subitem_source_identifier_type":"NCID"}]},"item_7_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_7_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐藤, 友昭","creatorNameLang":"ja"},{"creatorName":"Sato, Tomoaki","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"西川, 殷維","creatorNameLang":"ja"},{"creatorName":"Nishikawa, Takashige","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-27"}],"displaytype":"detail","fileDate":[{"fileDateType":"Issued","fileDateValue":"2008-03-26"}],"filename":"28-9.pdf","filesize":[{"value":"101.7 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"28-9.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/1633/files/28-9.pdf"},"version_id":"591622b6-5728-4419-82b5-4086656fe9ef"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"AVP1-9","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"AVP4-9","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"NC-1900","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"memory","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"passive avoidance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"radial maze","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"vasopressin receptor","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"PKC","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Effects of neuroactive peptides, vasopressin, vasopressin fragments, and its analog (NC-1900) on learning and memory","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Effects of neuroactive peptides, vasopressin, vasopressin fragments, and its analog (NC-1900) on learning and memory","subitem_title_language":"en"}]},"item_type_id":"7","owner":"29","path":["65","4807"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-10-05"},"publish_date":"2010-10-05","publish_status":"0","recid":"1633","relation_version_is_last":true,"title":["Effects of neuroactive peptides, vasopressin, vasopressin fragments, and its analog (NC-1900) on learning and memory"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2025-07-30T09:28:52.386632+00:00"}