{"created":"2025-05-23T02:57:06.943317+00:00","id":2001022,"links":{},"metadata":{"_buckets":{"deposit":"5b5458f6-fad1-492e-8f35-fd88b7dc0f65"},"_deposit":{"created_by":24,"id":"2001022","owners":[24],"pid":{"revision_id":0,"type":"depid","value":"2001022"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:02001022","sets":["168:169"]},"author_link":["15892"],"item_5_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2025-03-11","subitem_date_issued_type":"Collected"}]},"item_5_date_granted_54":{"attribute_name":"学位授与年月日 ","attribute_value_mlt":[{"subitem_dategranted":"2025-03-25"}]},"item_5_degree_grantor_53":{"attribute_name":"学位授与機関","attribute_value_mlt":[{"subitem_degreegrantor":[{"subitem_degreegrantor_language":"ja","subitem_degreegrantor_name":"鹿児島大学"}],"subitem_degreegrantor_identifier":[{"subitem_degreegrantor_identifier_name":"17701","subitem_degreegrantor_identifier_scheme":"kakenhi"}]}]},"item_5_degree_name_42":{"attribute_name":"学位名","attribute_value_mlt":[{"subitem_degreename":"博士(保健学)","subitem_degreename_language":"ja"},{"subitem_degreename":"Doctor of Philosophy in Health Science","subitem_degreename_language":"en"}]},"item_5_description_17":{"attribute_name":"ファイル（説明）","attribute_value_mlt":[{"subitem_description":"博士論文全文, 博士論文要旨, 最終試験結果の要旨, 論文審査の要旨","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_5_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"The brachial-ankle pulse wave velocity (baPWV) is useful for evaluating arterial stiffness. No longitudinal studies have examined the association between multiple arterial stiffness risk factors and increased baPWV. We sought to identify factors associated with baPWV ≥1400 cm/s within 5 years and create an equation and simple risk score to predict its occurrence, using data from a large-scale Japanese health examination database. Of 10,284 participants aged 30–69 years for whom follow-up data were available over a 5-year period, 3394 men and 2710 women with baseline baPWV<1400 cm/s were analyzed. We used age, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), fasting blood sugar (FBS), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), triglyceride (TG), estimated glomerular filtration rate (eGFR), habitual exercise, habitual drinking, and smoking history as variables. In the multivariate logistic regression analysis, baPWV≥1400 cm/s was associated significantly with age, BMI, SBP, DBP, HR, FBS, and TG in men and age, SBP, DBP, HR, and smoking history in women. A prediction score based on these factors yielded an area under the curve (AUC) for the 5-year incidence of baPWV≥1400 cm/s of 0.68 for men and 0.71 for women. Furthermore, a risk prediction equation for the 5-year incidence of baPWV≥1400 cm/s showed an AUC = 0.71 for men and 0.77 for women. The prediction equation and a simple prediction score are easy to implement clinically. The predictive ability of these scores and equations for arterial stiffness should be validated in prospective studies.","subitem_description_language":"en","subitem_description_type":"Other"},{"subitem_description":"Naoko Inadome, Shin Kawasoe, Masaaki Miyata, Takuro Kubozono, Satoko Ojima, Ryuko Mori, Hironori Miyahara, Koichi Tokushige, Mitsuru Ohishi\nRisk prediction score and equation for progression of arterial stiffness using Japanese longitudinal health examination data\nHypertension Research, 48, 1690-1701 (2025)\nhttps://doi.org/10.1038/s41440-024-02057-z","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_5_dissertation_number_55":{"attribute_name":"学位授与番号","attribute_value_mlt":[{"subitem_dissertationnumber":"甲保研第48号"}]},"item_5_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"Springer Nature","subitem_publisher_language":"en"},{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"}]},"item_5_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"【指導教員：宮田昌明】"}]},"item_5_text_47":{"attribute_name":"date.appl","attribute_value_mlt":[{"subitem_text_language":"ja","subitem_text_value":"【学位申請日】2024-12-12"}]},"item_5_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"稻留, 直子","creatorNameLang":"ja"},{"creatorName":"Inadome, Naoko","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"15892","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-05-23"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2025-03-11"}],"filename":"Diss_INADOME_Naoko_4721700016_2024.pdf","filesize":[{"value":"780.3 KB"}],"format":"application/pdf","licensetype":"license_0","mimetype":"application/pdf","url":{"label":"Diss_INADOME_Naoko_4721700016_2024.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/2001022/files/Diss_INADOME_Naoko_4721700016_2024.pdf"},"version_id":"b92f0bd0-3890-4452-acc0-be2964de5d85"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-05-23"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2025-03-11"}],"filename":"Abstract_INADOME_Naoko_4721700016_2024.pdf","filesize":[{"value":"362.7 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KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Result_INADOME_Naoko_hok_48.pdf","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/2001022/files/Result_INADOME_Naoko_hok_48.pdf"},"version_id":"bd097d9c-d555-46d7-9bbf-9ef7fc294aea"},{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2025-05-23"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2025-03-11"}],"filename":"Comment_INADOME_Naoko_hok_48.pdf","filesize":[{"value":"52.7 KB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"Comment_INADOME_Naoko_hok_48.pdf","objectType":"other","url":"https://ir.kagoshima-u.ac.jp/record/2001022/files/Comment_INADOME_Naoko_hok_48.pdf"},"version_id":"52f2f554-9d25-4d70-b31e-549256de2a5f"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Arterial stiffness","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"baPWV","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Prediction equation","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Prediction score","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"doctoral thesis","resourceuri":"http://purl.org/coar/resource_type/c_db06"}]},"item_title":"Risk prediction score and equation for progression of arterial stiffness using Japanese longitudinal health examination data","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Risk prediction score and equation for progression of arterial stiffness using Japanese longitudinal health examination data","subitem_title_language":"en"},{"subitem_title":"日本人の縦断的健康診断データを用いた動脈硬化進行のリスク予測スコアと予測式","subitem_title_language":"ja"}]},"item_type_id":"5","owner":"24","path":["169"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2025-05-23"},"publish_date":"2025-05-23","publish_status":"0","recid":"2001022","relation_version_is_last":true,"title":["Risk prediction score and equation for progression of arterial stiffness using Japanese longitudinal health examination data"],"weko_creator_id":"24","weko_shared_id":-1},"updated":"2025-05-23T03:13:50.850478+00:00"}