{"created":"2023-07-25T08:02:30.875196+00:00","id":214,"links":{},"metadata":{"_buckets":{"deposit":"3723fd27-a375-46c9-9ce0-5c41eef7376d"},"_deposit":{"created_by":18,"id":"214","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"214"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00000214","sets":["228:260:5594","31:32:33:34"]},"author_link":["108142","108143","108144","108145","108146","108147"],"item_6_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1997","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"31","bibliographicPageStart":"17","bibliographicVolumeNumber":"18","bibliographic_titles":[{"bibliographic_title":"南太平洋研究","bibliographic_titleLang":"ja"},{"bibliographic_title":"South Pacific Study","bibliographic_titleLang":"en"}]}]},"item_6_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"1997-01-01","subitem_date_issued_type":"Issued"}]},"item_6_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Previously we proposed a hypothesis that activation of blood coagulability in the intraosseous blood vessels contr ibutes impor tantly to produce decompression sickness (DCS) including dysbaric osteonecrosis (DON) after a hyperbar ic exposure. This paper presents evidence suppor ting this hypothesis. Crossbred, adult, female sheep were exposed to a three-hour exposure at 2.8-3.2 atm abs, using an experimental hyperbar ic chamber . They showed signs of bends in various legs soon after the exposure.\nEight weeks after decompression insult, more or less marked and extensive pathologic findings of the bone mar row tissue wer e noted at the time of autopsy in their tibiae. In three tibiae of seven exper imental ・・sheep, a wide spread necrosis was found in the bone mar row, particular ly in the upper half of the shaft. ・・\nIn one of them, the large branches including the main ascending branch of the intraosseous nutrient artery were obliterated by organized thrombi at a little above the middle portion of the shaft of the right tibia. This arterial lesion seemed closely related to a widespread necrosis of the bone mar row of upper half of the shaft. Another conspicuous finding was formation of cutting cones, a repair process, observed in the cortical compact bone. Through formation of cutting cones, blood supply of the cortical bone recovered from the periosteum resulting in an active organization of necrotic bone mar row, where active formation of woven bone was observed. These suggest that provocative hyperbaric exposure can cause\narterial thrombosis to produce early stage of necrosis of the bone tissues, and the subsequent repair processes can exaggerate the features of DON.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_6_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09160752","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN10088628","subitem_source_identifier_type":"NCID"}]},"item_6_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kitano, Motoo","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Lehner, Charles E.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Taya, Yasushi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ozaki, Hiroshi S.","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takenaka, Masami","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawashima, Mahito","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-27"}],"displaytype":"detail","filename":"P17-P31.pdf","filesize":[{"value":"246.4 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"P17-P31.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/214/files/P17-P31.pdf"},"version_id":"5ba324a9-d350-43b7-a42d-3a1a1519a243"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"sheep tibia","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"hyperbar ic exposure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"decompression sickness (DCS)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"dysbaric osteonecrosis (DON)","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"thrombosis","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"increased tissue pressure","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"intraosseous nutrient artery","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"cutting cone","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Histopathological Study on Dysbaric Osteonecrosis (DON) in Tibiae of Sheep with a Hyperbaric Exposure","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Histopathological Study on Dysbaric Osteonecrosis (DON) in Tibiae of Sheep with a Hyperbaric Exposure","subitem_title_language":"en"}]},"item_type_id":"6","owner":"18","path":["5594","34"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2008-07-07"},"publish_date":"2008-07-07","publish_status":"0","recid":"214","relation_version_is_last":true,"title":["Histopathological Study on Dysbaric Osteonecrosis (DON) in Tibiae of Sheep with a Hyperbaric Exposure"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-02-26T00:35:35.702167+00:00"}