{"created":"2023-07-25T08:04:06.548502+00:00","id":2216,"links":{},"metadata":{"_buckets":{"deposit":"a1ec3bb2-d475-4ec7-a35c-7fc87eb22f30"},"_deposit":{"created_by":29,"id":"2216","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"2216"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00002216","sets":["82:83"]},"author_link":["11709"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-05-30","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2008-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号:20591282 研究代表者:西順一郎 (鹿児島大学医学部・歯学部附属病院講師)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"転写調節因子AggRを保有する腸管凝集性大腸菌Enteroaggregative Esherichia coli(EAEC)の検出頻度は、下痢症患児由来大腸菌2,417株中76株(3.1%)であった。菌体表層抗原Aapの検出頻度はEAECでは81.6%と高く、アミノ酸配列はよく保存されていた。イムノクロマト法によるEAEC検出に利用するために、Aapのリコンビナント蛋白を用いて抗Aap抗体を作成し、EAECへの反応性を確認できた。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"We demonstrated that the incidence of typical enteroaggregative Esherichia coli (EAEC) among E. coli strains isolated from diarrheal children was 3.1% (76/2,417). The incidence of suface-layer protein Aap was 81.6% among typical EAEC strains, and its amino-acid sequences were well conserved. We successfully prepared anti-Aap antibodies using recombinant Aap protein, which can be applied for a rapid immunochromatographic detection system of EAEC.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"493","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"20591282"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"西, 順一郎","creatorNameLang":"ja"},{"creatorName":"NISHI, Junichiro","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"11709","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000040295241","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-27"}],"displaytype":"detail","fileDate":[{"fileDateType":"Collected","fileDateValue":"2011-05-30"}],"filename":"20591282seika.pdf","filesize":[{"value":"418.5 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"20591282seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/2216/files/20591282seika.pdf"},"version_id":"c3420523-00ab-4232-8019-6964157754b3"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"小児","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"下痢症","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"下痢原性大腸菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"腸管凝集性大腸菌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"新興病原菌としての腸管凝集性大腸菌の分子疫学研究とイムノクロマト迅速診断法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新興病原菌としての腸管凝集性大腸菌の分子疫学研究とイムノクロマト迅速診断法の開発","subitem_title_language":"ja"},{"subitem_title":"Molecular-epidemiological study of an emerging pathogen enteroaggregative Eschelichia coli and development of rapid diagnosis using immunochromatography","subitem_title_language":"en"}]},"item_type_id":"8","owner":"29","path":["83"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"2216","relation_version_is_last":true,"title":["新興病原菌としての腸管凝集性大腸菌の分子疫学研究とイムノクロマト迅速診断法の開発"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2025-08-18T06:52:12.157789+00:00"}