{"created":"2023-07-25T08:04:06.973886+00:00","id":2226,"links":{},"metadata":{"_buckets":{"deposit":"6eed3d1e-675f-49d2-b338-daf1dee30fdd"},"_deposit":{"created_by":3,"id":"2226","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"2226"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00002226","sets":[]},"author_link":["117843","11752","117844"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Development of protection for systemic and oral infection by control of oral microbes"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"コウクウ ジョウザイ サイキンソウ ノ コントロール ニヨル コウクウ オヨビ ゼンシンセイ カンセン ボウギョホウ ノ コウチク ト ソノ オウヨウ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-05-31"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2008-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号：20592460　研究代表者：山口泰平 (鹿児島大学大学院医歯学総合研究科准教授)","subitem_description_type":"Other"},{"subitem_description":"インテーメディウスは口腔常在菌のひとつで全身性の化膿性病変をひき起こす。一部の菌は線毛を持っていた。この線毛遺伝子は線毛オペロンを形成し、４つの遺伝子を含んでいた。主要な遺伝子は486アミノ酸からなっていた。アンギノーサスレンサ球菌郡の中では血清型ｇとuntypableだけがこの遺伝子を持っていた。ノックアウト変異体は唾液中での凝集活性は失っていた。一方唾液凝集素への菌の付着活性は野生型と比較して65％に低下していた。","subitem_description_type":"Other"},{"subitem_description":"Streptococcus intermedius is an oral commensal and a cause of systemic pyogenic disease. A part of the organism possessed curly-like fimbriae. Genomic analyses showed that the operon of the fimbriae was a typical pilus gene operon and constructed of at least 4 ORFs. A fimI was predicted to be the structural subunit encoding the 486-amino acid protein, FimI. Strains of the Streptococcus anginosus group containing the fimI gene were restricted to serotype g and untypable,. Knockout mutants within fimI did not participate in saliva-mediated aggregation either. The adherent activity of mutants toward plastic wells coated with salivary agglutinin was about 65% that of the parent strain.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ヤマグチ, タイヘイ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"YAMAGUCHI, Taihei"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"20592460"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"山口, 泰平"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-27"}],"displaytype":"detail","filename":"20592460seika.pdf","filesize":[{"value":"277.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20592460seika.pdf","url":"https://ir.kagoshima-u.ac.jp/record/2226/files/20592460seika.pdf"},"version_id":"09278470-be57-448e-9c4f-14be3bd6a229"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"口腔常在菌","subitem_subject_scheme":"Other"},{"subitem_subject":"唾液","subitem_subject_scheme":"Other"},{"subitem_subject":"凝集","subitem_subject_scheme":"Other"},{"subitem_subject":"付着","subitem_subject_scheme":"Other"},{"subitem_subject":"凝集素","subitem_subject_scheme":"Other"},{"subitem_subject":"カルシウム","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"口腔常在細菌叢のコントロールによる口腔および全身性感染防御法の構築とその応用","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"口腔常在細菌叢のコントロールによる口腔および全身性感染防御法の構築とその応用"}]},"item_type_id":"8","owner":"3","path":["80"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"2226","relation_version_is_last":true,"title":["口腔常在細菌叢のコントロールによる口腔および全身性感染防御法の構築とその応用"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-12-25T07:18:49.018043+00:00"}