@article{oai:ir.kagoshima-u.ac.jp:00002836,
 author = {西村, 正宏 and Nishimura, Masahiro},
 journal = {鹿児島大学歯学部紀要},
 month = {Mar},
 note = {This review shows a summary of our previous studies concerning how to augment alveolar bone ridge by minimum intervention using autologous alveolar bone derived mesenchymal stem cells (MSC) and scaffolds. We successfully collected MSC from alveolar bone marrow using newly developed puncture needle, and expanded them in vitro. We have developed serum free culture medium and found several new initial osteogenic markers and new resistance factors for external stimuli on MSC. Furthermore, we found several factor controlling MSC migration and osteogenic differentiation. We combined MSC with calcium phosphate scaffold and transplanted them into canine edentulous model and successfully observed osseointegration between augmented bone and implant. We are going to start alveolar bone augmentation treatment using alveolar bone marrow MSC/scaffold utilizing above mentioned techniques in the near future.},
 pages = {53--64},
 title = {顎骨骨髄間葉系幹細胞を用いた顎骨増生医療の開発},
 volume = {34},
 year = {2014}
}