@article{oai:ir.kagoshima-u.ac.jp:00004306,
 author = {TATENO, Taro and UENO, Shinichi and SAKODA, Masahiko and KUBO, Fumitake and HIWATASHI, Kiyokazu and BABA, Yoshiro and BABA, Yasutaka and HASEGAWA, Susumu and TSUBOUCHI, Hirohito and NATSUGOE, Shoji},
 issue = {2},
 journal = {鹿児島大学医学雑誌, Medical journal of Kagoshima University},
 month = {},
 note = {Purpose: To clarify the prognostic factors for long-term survival by studying the clinical factors of 10-year survivors after initial treatment for hepatocellular carcinoma (HCC).
Methods: 713 Japanese patients who had received over 10 year’s observation after initial treatment for HCC were selected.
Differences in clinical factors between 10-year survivors and the remainder were studied. The multiple logistic regression model was used for multivariate analysis.
Results: Significant differences were noted between the groups in age, tumor number, vascular involvement, concordance of Milan Criteria (MC), Japanese tumor-node-metastasis stage, Child-Pugh stage (CP), HCV infection, serum α-fetoprotein level, and modality of initial treatment. Multivariate analysis showed that older age, out of MC, CP-B or -C, and initially treated other than by hepatectomy were independent risk factors for 10-year survival. If patients were within MC and CP-A, the overall 10-year survival rate of those initially treated by hepatectomy was 71%, and 49% for those with HCV infection.
Conclusions: Younger patients with initial HCC within MC and CP-A can expect long-term survival, if surgically resectable. Hepatectomy should be considered especially to HCC patients with HCV infection, if in these categories.},
 pages = {45--54},
 title = {Prognostic Factors of 10-Year Survivors after Initial Treatmentfor Hepatocellular Carcinoma, Determined in 713 Japanese Patientsin Relation to Indication of Liver Transplantation.},
 volume = {60},
 year = {2008}
}