{"created":"2023-07-25T08:06:21.474028+00:00","id":5092,"links":{},"metadata":{"_buckets":{"deposit":"3c65dad4-c3ef-4ea4-af47-d961efb35a5e"},"_deposit":{"created_by":3,"id":"5092","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5092"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00005092","sets":[]},"author_link":["117903","117904","13744"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Influences of the occlusion on gastroesophageal reflux disease and acid clearance in oral cavity, pharynx and esophagus during sleep"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"スイミンジ ノ コウクウ イントウ ショクドウ ナイ ノ サン ノ クリアランス ト サン カンレン ジョウブ ショウカキ シッカン ニ タイスル コウゴウ ノ エイキョウ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-31"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2008-2011年度科学研究費助成事業(科学研究費補助金(基盤研究(B)))研究成果報告書 課題番号：20390524　研究代表者：宮脇正一 (鹿児島大学大学院医歯学総合研究科教授)","subitem_description_type":"Other"},{"subitem_description":"良好な咬合と睡眠時の唾液流出率、口腔咽頭食道内の酸のクリアランス、酸関連上部消化器疾患との関連を調べた結果、(1) 骨格性下顎前突症患者では、胃食道逆流症（以下GERD症状）が有意に多く、咬合力は有意に弱く、咬合接触面積は有意に狭く、咬合機能の低下とGERD症状が関連していた。(2) 成人健常者の食道内へ、人為的な酸の注入を行うと、睡眠時ブラキシズムが惹起された。(3) ブラキシズム患者に、上部消化管の内視鏡検査を行った結果、胃食道逆流症（以下GERD）の罹患率が有意に高かったが、食道炎の程度や消化器症状は比較的軽度であった。以上の一連の研究により、良好な咬合は、唾液の流出率を増加させ、咽頭や食道内の酸のクリアランスを高め、GERDの発症を抑制する可能性が示唆された。","subitem_description_type":"Other"},{"subitem_description":"In the present study, we hypothesized that good occlusion increases the acid clearance in the oral cavity, pharynx and esophagus, leading to the prohibition of the gastroesophageal reflux disease (GERD). (1) The results of the investigation of masticatory functions in patients with skeletal Class III malocclusion suggested that GERD symptoms were observed more often than in normal subjects. (2) The results of the investigation of the effects of intra-esophageal infusions of 5-mL acidic solution (0.1 N HCl) or saline to the healthy adults suggested that sleep bruxism episodes were induced by esophageal acidification. (3) Bruxism patients (n=7) had high frequency of GERD with a mild esophagitis. These researches show good occlusion has associations with esophageal acidification, suppression of upper gastrointestinal disease.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ミヤワキ, ショウイチ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"MIYAWAKI, Shouichi"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"20390524"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宮脇, 正一"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"20390524seika.pdf","filesize":[{"value":"536.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20390524seika.pdf","url":"https://ir.kagoshima-u.ac.jp/record/5092/files/20390524seika.pdf"},"version_id":"904482e0-0098-46ed-b149-d9264fb49380"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ブラキシズム","subitem_subject_scheme":"Other"},{"subitem_subject":"胃食道逆流","subitem_subject_scheme":"Other"},{"subitem_subject":"GERD","subitem_subject_scheme":"Other"},{"subitem_subject":"酸","subitem_subject_scheme":"Other"},{"subitem_subject":"クリアランス","subitem_subject_scheme":"Other"},{"subitem_subject":"咬合","subitem_subject_scheme":"Other"},{"subitem_subject":"骨格性下顎前突","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"睡眠時の口腔咽頭食道内の酸のクリアランスと酸関連上部消化器疾患に対する咬合の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"睡眠時の口腔咽頭食道内の酸のクリアランスと酸関連上部消化器疾患に対する咬合の影響"}]},"item_type_id":"8","owner":"3","path":["80"],"pubdate":{"attribute_name":"公開日","attribute_value":"2014-12-22"},"publish_date":"2014-12-22","publish_status":"0","recid":"5092","relation_version_is_last":true,"title":["睡眠時の口腔咽頭食道内の酸のクリアランスと酸関連上部消化器疾患に対する咬合の影響"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-12-25T07:18:42.547901+00:00"}