{"created":"2023-07-25T08:06:22.746914+00:00","id":5121,"links":{},"metadata":{"_buckets":{"deposit":"efad1931-0106-4115-8549-1b4e98a1b8b7"},"_deposit":{"created_by":18,"id":"5121","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"5121"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00005121","sets":["57:80"]},"author_link":["2140"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-30","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2011-2011年度科学研究費助成事業(学術研究助成基金助成金(挑戦的萌芽))研究成果報告書　課題番号：23659657　研究代表者：夏越祥次 (鹿児島大学大学院医歯学総合研究科教授)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"食道癌患者37例と健常者11例対象とし、血清中の糖鎖の網羅的解析を行い、食道癌に特異的な糖鎖マーカーを検索した。得られた糖鎖の発現パターンをもとに、健常者群と食道癌患者群との間でOPLS法による層別化が可能であった。健常者群と食道癌患者群間で、両者の層別化が可能な発現糖鎖が6つ抽出可能であった。その6糖鎖から食道癌患者を69.7%の正診率で判別することが可能であった。これらの糖鎖は食道癌に特異的マーカーとして利用できると考えられた。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"We analyzed the serum N-glycan in 37 esophageal cancer patients and 11 healthy volunteers. N-glycan expression by using OPLS method was stratified between esophageal cancer patients and healthy volunteers on the base of glycan expression pattern, We extracted six N-glycan with statistical significance between esophageal cancer patients and healthy volunteers. According to these six markers, the accuracy rate was 69.7% to detect the esophageal cancer. These results show that six N-glycan may be a useful markers in detection of esophageal cancer.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"494","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"23659657"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"夏越, 祥次","creatorNameLang":"ja"},{"creatorName":"NATSUGOE, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"2140","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000070237577","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"23659657seika.pdf","filesize":[{"value":"431.5 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"23659657seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/5121/files/23659657seika.pdf"},"version_id":"cde46113-d597-430f-9696-0138fd59fa61"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"食道癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"胃癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"大腸癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"膵臓癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"N結合型糖鎖","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発","subitem_title_language":"ja"},{"subitem_title":"Search of organ specific tumor markers by N-glycan expression","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["80"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-12-22"},"publish_date":"2014-12-22","publish_status":"0","recid":"5121","relation_version_is_last":true,"title":["N型糖鎖を用いた臓器特異的癌腫瘍マーカーの開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-05-24T00:24:05.401411+00:00"}