@article{oai:ir.kagoshima-u.ac.jp:00005504,
 author = {Kita, Yoshiaki and 喜多, 芳昭 and Okumura, Hiroshi and 奥村, 浩 and Uchikado, Yasuto and 内門, 泰斗 and Sasaki, Ken and 佐々木, 健 and Omoto, Itaru and 尾本, 至 and Matsumoto, Masataka and 松本, 正隆 and Setoyama, Tetsuro and 瀬戸山, 徹郎 and Tanoue, Kiyonori and 田上, 聖徳 and Mori, Shinichiro and 盛, 真一郎 and Owaki, Tetsuhiro and 大脇, 哲洋 and Ishigami, Sumiya and 石神, 純也 and Ueno, Shinichi and 上野, 真一 and Kajiya, Yoriko and 加治屋, より子 and Natsugoe, Shoji and 夏越, 祥次},
 issue = {5},
 journal = {Annals of Surgical Oncology},
 month = {},
 note = {Purpose: To assess the clinical usefulness and significance of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in superficial esophageal squamous cell carcinoma (ESCC).
Methods: We examined FDG-PET for 80 consecutive patients with superficial ESCC without neoadjuvant treatment. Fifty-seven patients underwent radical esophagectomy, and 23 patients received endoscopic resection. The FDG uptake index was evaluated with clinicopathological findings, and glucose transporter 1 (Glut-1) expression in primary tumors was examined immunohistochemically.
Results: The FDG uptake in primary tumors correlated with histology, depth of tumor invasion, lymph node metastasis, lymphatic invasion, vascular invasion, and Glut-1 expression. All patients with more than 4.4 maximum standardized uptake value (SUVmax) had deeper invasion of submucosa. Among 16 patients with lymph node metastasis, only two were found to have lymph node metastasis. FDG uptake, depth of tumor invasion, lymph node metastasis, and histology were found to be prognostic factors, and histology was an independent prognostic factor. In FDG uptake–positive patients, depth of tumor invasion and histology were prognostic factors.
Conclusions: FDG-PET is useful for diagnosing tumors with deeper invasion of submucosa and is helpful in making decisions regarding endoscopic treatment for superficial ESCC. Patients with FDG uptake–positive disease, deeper invasion of submucosa, poorly differentiated tumor, and poor prognosis should receive multimodal treatment.},
 pages = {1646--1652},
 title = {Clinical Significance of 18F-fluorodeoxyglucose Positron Emission Tomography in Superficial Esophageal Squamous Cell Carcinoma},
 volume = {20},
 year = {2013},
 yomi = {キタ, ヨシアキ and オクムラ, ヒロシ and ウチカド, ヤスト and ササキ, ケン and オモト, イタル and マツモト, マサタカ and セトヤマ, テツロウ and タノウエ, キヨノリ and モリ, シンイチロウ and オオワキ, テツヒロ and イシガミ, スミヤ and ウエノ, シンイチ and カジヤ, ヨリコ and ナツゴエ, ショウジ}
}