{"created":"2023-07-25T08:06:45.535795+00:00","id":5647,"links":{},"metadata":{"_buckets":{"deposit":"e33e5906-a7b6-43ba-886a-3c2916d2df04"},"_deposit":{"created_by":18,"id":"5647","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"5647"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00005647","sets":["131:167"]},"author_link":["106434","106435","106436","106437","106438"],"item_6_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2006","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"890","bibliographicPageStart":"885","bibliographicVolumeNumber":"68","bibliographic_titles":[{"bibliographic_title":"The Journal of Veterinary Medical Science","bibliographic_titleLang":"en"}]}]},"item_6_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2006-09-05","subitem_date_issued_type":"Issued"}]},"item_6_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Molecular cloning of feline lung resistance-related protein (LRP) was performed to evaluate the relationship between its expression level and drug resistance against chemotherapeutics. The nucleotide sequence of the coding region of feline LRP cDNA was found to be 2670-bp long and to show 84.2–92.6% homology to its human, mouse, and rat counterparts. The expression level of feline LRP mRNA was relatively high in lung, jejunum, and colon. An adriamycin (ADM)-resistant feline lymphoma subline, FT-1/ADM, showed a high level of MDR1 mRNA expression compared with parental FT-1 cells. However, no relationship was observed between the drug-resistant phenotype and the LRP mRNA expression level. Although no direct contribution of LRP to the development of the drug-resistant phenotype was observed, further investigation is advisable.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_6_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"公益社団法人日本獣医学会","subitem_publisher_language":"ja"}]},"item_6_relation_11":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1292/jvms.68.885","subitem_relation_type_select":"DOI"}}]},"item_6_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"本文データは日本獣医学会の許諾に基づきJ-STAGEから複製したものである","subitem_rights_language":"ja"}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"09167250","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA10796138","subitem_source_identifier_type":"NCID"}]},"item_6_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"467","subitem_subject_scheme":"NDC"}]},"item_6_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fukushima, Kenjiro","creatorNameLang":"en"},{"creatorName":"福島, 建次郎","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"106434","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Okai, Yoshiko","creatorNameLang":"en"},{"creatorName":"岡井, 佳子","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"106435","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Matsuura, Shinobu","creatorNameLang":"en"},{"creatorName":"松浦, 忍","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"106436","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsujimoto, Hajime","creatorNameLang":"en"},{"creatorName":"辻本, 元","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"106437","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Endo, Yasuyuki","creatorNameLang":"en"},{"creatorName":"遠藤, 泰之","creatorNameLang":"ja"}],"nameIdentifiers":[{"nameIdentifier":"106438","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA and its Expression in a Feline Lymphoma Cell Line and Adriamycin-Resistant Subline.pdf","filesize":[{"value":"309.0 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA and its Expression in a Feline Lymphoma Cell Line and Adriamycin-Resistant Subline.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/5647/files/Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA and its Expression in a Feline Lymphoma Cell Line and Adriamycin-Resistant Subline.pdf"},"version_id":"fb812af8-34ae-4db1-87f6-a7b2d71d3f0b"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"feline","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"LRP","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"MDR","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA","subitem_title_language":"en"}]},"item_type_id":"6","owner":"18","path":["167"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-02-10"},"publish_date":"2014-02-10","publish_status":"0","recid":"5647","relation_version_is_last":true,"title":["Molecular Cloning of Feline Lung Resistance-Related Protein (LRP) cDNA"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-01-30T06:26:54.328546+00:00"}