@article{oai:ir.kagoshima-u.ac.jp:00005649,
 author = {Sakuma, Masato and 佐久間, 暢人 and Nakahara, Yoshitaka and 中原, 佳孝 and Suzuki, Hiroyuki and 鈴木, 寛之 and Uchimura, Masato and 内村, 正人 and Sekiya, Zin and 関屋, 仁 and Setoguchi, Asuka and 瀬戸口, 明日香 and Endo, Yasuyuki and 遠藤, 泰之},
 issue = {6},
 journal = {The Journal of Veterinary Medical Science},
 month = {},
 note = {We present a clinical overview of a dog with acute onset of Hepatozoon canis infection. A stray female beagle dog of unknown age was referred to Kagoshima University showing anemia. Blood tests revealed the presence of anemia, thrombocytopenia, hyperproteinemia, polyclonal gammopathy, hypoalbuminemia, and elevated creatine kinase and alkaline phosphatase activities. In addition, capsule-like organisms were detected in the ytoplasm of approximately 50% of neutrophils in blood smears. H. canis infection was confirmed by polymerase chain reaction and DNA sequencing analyses. Amplified DNA fragments revealed 100% identity to the 18S ribosomal RNA gene of H. canis. The clinical symptoms improved after the administration of antibiotics. Hepatozoonosis in dogs is rare, but veterinarians should be alert to its possible acute onset.},
 pages = {835--838},
 title = {A Case Report: a Dog with Acute Onset of Hepatozoon canis Infection},
 volume = {71},
 year = {2009}
}