{"created":"2023-07-25T08:07:32.155165+00:00","id":6694,"links":{},"metadata":{"_buckets":{"deposit":"b58d008e-2fb6-4362-add9-04e641547351"},"_deposit":{"created_by":29,"id":"6694","owners":[29],"pid":{"revision_id":0,"type":"depid","value":"6694"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00006694","sets":["228:270:5677","43:44"]},"author_link":["93482","93483","93484","93485"],"item_7_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2005-02-20","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"24","bibliographicPageStart":"17","bibliographicVolumeNumber":"40","bibliographic_titles":[{"bibliographic_title":"Memoirs of the Faculty of Agriculture, Kagoshima University","bibliographic_titleLang":"en"}]}]},"item_7_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2005-02-20","subitem_date_issued_type":"Issued"}]},"item_7_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"Perchloric acid-soluble protein (PSP) is highly conserved during evolution from bacteria to mammals. Although PSP has been recognized as an inhibitor of translation and a μ-calpain activator, its precise biological role has not yet been elucidated. Because the μ-calpain has been reported to act as an inducer of apoptosis in endoplasmic reticulum (ER)-stressed cells, we speculated that PSP might be associated with ER-stress. In this study, we used immunoelectron microscopy to demonstrate that PSP locates on the ER membrane. Moreover, various ER-stressors (thapsigargin, A23187, tunicamycin, brefeldin A and cisplatin) provoked dramatic change in localization of PSP from ER to nuclei. These results suggest that PSP is a novel ER-stress associated protein and may induce attenuation of translation and/or apoptosis in ER-stressed cells.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_7_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"04530853","subitem_source_identifier_type":"PISSN"}]},"item_7_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA00732376","subitem_source_identifier_type":"NCID"}]},"item_7_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"610","subitem_subject_scheme":"NDC"}]},"item_7_subject_20":{"attribute_name":"NIIsubject","attribute_value_mlt":[{"subitem_subject":"農学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_7_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_access_right":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"KANOUCHI, Hiroaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93482","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"TAGA, Masaki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93483","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"MATSUMOTO, Mitsuharu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93484","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"OKA, Tatsuzo","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"93485","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","fileDate":[{"fileDateType":"Issued","fileDateValue":"2005-02-20"}],"filename":"KJ00004161864.pdf","filesize":[{"value":"704.9 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"KJ00004161864.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/6694/files/KJ00004161864.pdf"},"version_id":"6d383085-ad10-4df3-a581-5ab8b8bdf891"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"perchloric acid-soluble protein","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"p14.5","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"μ-calpain","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"endoplasmic reticulum","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ER-stress","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"thapsigargin","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Perchloric acid-soluble protein is accumulated in nuclei by ER-stressors","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Perchloric acid-soluble protein is accumulated in nuclei by ER-stressors","subitem_title_language":"en"}]},"item_type_id":"7","owner":"29","path":["44","5677"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2007-04-24"},"publish_date":"2007-04-24","publish_status":"0","recid":"6694","relation_version_is_last":true,"title":["Perchloric acid-soluble protein is accumulated in nuclei by ER-stressors"],"weko_creator_id":"29","weko_shared_id":-1},"updated":"2025-01-22T01:21:27.034597+00:00"}