{"created":"2023-07-25T08:07:37.134619+00:00","id":6796,"links":{},"metadata":{"_buckets":{"deposit":"3506c7ca-1a6f-4882-8799-fd8f62d26f9e"},"_deposit":{"created_by":18,"id":"6796","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"6796"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00006796","sets":["57:78"]},"author_link":["117095","117096","117097","117098","117099"],"item_6_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-01-01","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"21","bibliographicPageStart":"14","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"Dendritic cells","bibliographic_titleLang":"en"}]}]},"item_6_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"1996-01-01","subitem_date_issued_type":"Issued"}]},"item_6_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"ln a HTLV-1 carrier Japanese man gastric T cell-rich B cell lymphoma occurred at 67 years of age and nodal T cell malignant lymphoma appeared at 72 years of age. The gastric T-cell rich B-cell Iymphoma formed an ulcerated tumor in the posterior wall of the body, involving up to the serosa and regional lymph nodes. A few lymphoma cells had cytoplasmic monoclonal κ and λ type immunoglobulin. Signals of HTLV-l pX Tax DNA sequence and stains of three antibodies against HTLV-1-encoded proteins  (gp46env, p40tax and p19gag) in some lymphoma cells suggested that this gastric lymphoma was a HTLV-1-related case. Six years later, large cell type T-cell malignant \nlymphoma occurred in left inguinal lymph node. Many S100+ dendritic cells and ysozyme+ cells were intermingling among the lymphoma cells. Some epithelioid cells among the lymphoma cells showed weak stains of the three antibodies against HTLV-l-encoded proteins. The PCR analysis showed oligoclonal rearrangement bands of TCRβ gene in the agar-gel electrophoresis. After three months' follow-up without chemotherapy, recurrent swelling of left inguinal lymph node and splenomegaly appeared. After chemotherapy the biopsied left inguinal lymph node showed necrosis and residual T cell malignant lymphoma. The uncommon features such as many T cells in the gastric lymphoma and many S100+ cells, many lysozyme+ cells and oligoclonal rearrangement of TCRβ gene in the nodal T-cell lymphoma might be induced by HTLV-1 infection. The patient has survived without any complaints. The HTLV-l-related lymphoid malignancies other than adult T-cell leukemia/lymphoma would be not-aggressive and might be the diseases in the microenvironment under the immunocompromised state in HTLV-1 carrier.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_6_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"日本樹状細胞研究会","subitem_publisher_language":"ja"},{"subitem_publisher":"Japanese Dendritic Cells Society","subitem_publisher_language":"en"}]},"item_6_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AA11039557","subitem_source_identifier_type":"NCID"}]},"item_6_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"490","subitem_subject_scheme":"NDC"}]},"item_6_subject_20":{"attribute_name":"NIIsubject","attribute_value_mlt":[{"subitem_subject":"医学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_6_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hasui, Kazuhisa","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"117095","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Shirahama, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"117096","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sueyoshi, Kazunobu","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"117097","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sato, Eiichi","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"117098","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Imakuma, Mitsuru","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"117099","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"DC(Hasui)1996.pdf","filesize":[{"value":"351.3 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"DC(Hasui)1996.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/6796/files/DC(Hasui)1996.pdf"},"version_id":"4f9b8ed3-9f4a-4efa-9ac0-0fdf31cd3b57"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"HTLV-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"malignant lymphoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pathology","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"histochemistry","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"polymerase chain reaction","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier","subitem_title_language":"en"}]},"item_type_id":"6","owner":"18","path":["78"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2010-04-13"},"publish_date":"2010-04-13","publish_status":"0","recid":"6796","relation_version_is_last":true,"title":["Metachronous occurrence of gastric T-cell rich B-cell lymphoma and nodal T-cell lymphoma in a HTLV-1 carrier"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-02-07T06:19:35.765100+00:00"}