@article{oai:ir.kagoshima-u.ac.jp:00007319,
 author = {Mitsuiki, Shinji and Takasugi, Mikako and Goto, Masatoshi and Kanouchi, Hiroaki and Oka, Tatsuzo},
 journal = {鹿兒島大學農學部學術報告=Bulletin of the Faculty of Agriculture, Kagoshima University},
 month = {2016-10-28},
 note = {It is suggested that the keratinolytic activity of proteases are associated with the degrading activity
 of the abnormal type prion protein (PrPSc). We tried to analyze the keratinolytic properties of the PrPSc-
degrading enzyme E77. E77 showed a much greater keratinolytic activity than proteinase K and 
subtilisin. The maximum activity of keratin was observed at a pH value of 12.0 at 65°C. E77 also
 showed a pH-independent adsorbability for keratin. These profiles of E77 were the same as the PrPSc
-degrading enzyme NAPase, except for high alkaline conditions. E77 and NAPase showed lower
 collagenolytic and elastinolytic specificities.},
 pages = {37--42},
 title = {Keratinolytic Properties of PrPSc-degrading Enzyme E77},
 volume = {59},
 year = {}
}