@article{oai:ir.kagoshima-u.ac.jp:00000746,
 author = {KANAZAWA, Akio and TESHIMA, Shin-ichi and TOKIWA, Shigeru and IMATANAKA, Nobuya},
 issue = {1},
 journal = {鹿児島大学水産学部紀要=Memoirs of Faculty of Fisheries Kagoshima University},
 month = {2016-10-27},
 note = {Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) methylesters (ME) were prepared
from a squid-liver oil and their hypocholesterolemic activities examined with rats. The supplement
of 0.3% EPA-ME to the diet containing 1.0% cholesterol and 4.0% butter as lipids reduced a serum-cholesterol
level markedly, whereas DHA-ME gave almost no effect on the serum-cholesterol level.
Both EPA-ME and DHA-ME reduced the liver-cholesterol level as effectively as linoleic acid did.
The supplement of small amounts of EPA-ME was also effective in lowering the serum-cholesterol
level; a dose of 0.03% EPA-ME suppressed by 60.7% the elevation of serum-cholesterol level.},
 pages = {73--78},
 title = {Hypocholesterolemic Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid in Rats},
 volume = {33},
 year = {}
}