@article{oai:ir.kagoshima-u.ac.jp:00007574,
 author = {齋藤, 要 and 鮫島, 宗雄},
 issue = {2},
 journal = {鹿児島大学水産学部紀要=Memoirs of Faculty of Fisheries Kagoshima University},
 month = {2016-10-28},
 note = {The  authors researched into the antibiotic activity of the excellent mould isolated from  "  Katsuobushi", summarizing the results in Table  1-5, Fig.  1,-2, observing the following  phenomena: In Czapek solution some strains of A. rubcr and A.  rcpens produced the anti-biotic  substance inhibiting the growth of B. subtilis and other bacteria. This antibiotic substance  was removed from the culture-fluid and mycelia to ethyl-acetate and ether soluble fraction. Those fractions showed an inhibitory power 
against the growth of B.  subtilis at the dilution of  1:10,000-1.00,000 and against 
E.  colt at that of  1:1,000-40,000. Generally, the power of this substance against the growth  of Gram positive  bacteria(i.e. B.  mesentericzcs,  M.pyogenes  aureus) was more effective than that against Gram negative bacteria (i.e. P. vulgaris). 
 In manufacturing  "Katsuobushi", it is desirable that the antibiotic power is 
effective to the injurious fungi rather than to bacteria, but within the scope of these studies, the antibiotic power of the excellent mould against Rhizopus Delemar and A.  melleus  was not recognized. By applying the liquid chromatography upon the column of the active alumina, we separated several kinds of crude crystals from  the effective fraction.},
 pages = {56--61},
 title = {鰹節黴の生化学的研究 - I : 抗菌性について},
 volume = {3},
 year = {}
}