{"created":"2023-07-25T08:08:20.472877+00:00","id":7696,"links":{},"metadata":{"_buckets":{"deposit":"d8ef2d9b-529e-45fa-8179-8097f1cb3390"},"_deposit":{"created_by":3,"id":"7696","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7696"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00007696","sets":[]},"author_link":["74401","27928","74400"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Experimental analysis of the induction mechanism of atherosclerosis by oral biofilm bacteria as a possible new risk factor"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"シンキ リスク ファクター コウホ コウクウ バイオ フィルム サイキン ニヨル ドウミャク コウカ ユウハツ キジョ ノ ジッケンテキ カイメイ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-04-28"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2008-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号：20592459　研究代表者：長田恵美 (鹿児島大学大学院医歯学総合研究科助教)","subitem_description_type":"Other"},{"subitem_description":"口腔レンサ球菌は、健康な人の口の中に住んでいる細菌であるが、動脈硬化の患者さんにおいては、動脈硬化病巣からこの細菌が発見されている。我々は口腔レンサ球菌が、ヒト動脈内皮細胞（動脈の内側の細胞）に侵入すること、むし歯の原因菌を含む４種類の口腔レンサ球菌は、侵入した動脈内皮細胞にサイトカイン（動脈硬化を引き起こす物質）を作らせることを明らかにした。この結果から、口腔レンサ球菌は動脈硬化誘発に関与する可能性が示唆された。","subitem_description_type":"Other"},{"subitem_description":"Oral viridans group streptococci are the major commensal bacteria of the supragingival oral biofilm and have been detected in human atheromatous plaque. The oral streptococci tested were capable of invading HAECs. HAECs invaded by one of four kinds of oral streptococci including cariogenic bacterium produced more cytokine(s) than non-invaded HAECs. These results suggest that oral streptococci may participate in the pathogenesis of atherosclerosis.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ナガタ, エミ"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"NAGATA, Emi"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"20592459"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"長田, 恵美"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"20592459seika.pdf","filesize":[{"value":"274.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20592459seika.pdf","url":"https://ir.kagoshima-u.ac.jp/record/7696/files/20592459seika.pdf"},"version_id":"2a50447c-eead-45af-a5a1-670146cba6d5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"口腔細菌","subitem_subject_scheme":"Other"},{"subitem_subject":"バイオフィルム","subitem_subject_scheme":"Other"},{"subitem_subject":"感染症","subitem_subject_scheme":"Other"},{"subitem_subject":"動脈硬化","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"新規リスクファクター候補口腔バイオフィルム細菌による動脈硬化誘発機序の実験的解明","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"新規リスクファクター候補口腔バイオフィルム細菌による動脈硬化誘発機序の実験的解明"}]},"item_type_id":"8","owner":"3","path":["83"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"7696","relation_version_is_last":true,"title":["新規リスクファクター候補口腔バイオフィルム細菌による動脈硬化誘発機序の実験的解明"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-01-29T08:29:12.092075+00:00"}