{"created":"2023-07-25T08:08:20.731062+00:00","id":7702,"links":{},"metadata":{"_buckets":{"deposit":"9733d0f9-65fe-460d-ab00-805e2ceb0d1c"},"_deposit":{"created_by":3,"id":"7702","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7702"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00007702","sets":[]},"author_link":["117954","28542","117953"],"item_8_alternative_title_18":{"attribute_name":"別言語のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Mucin gene expression mechanism related to a new classification of pancreatobiliary neoplasms"}]},"item_8_alternative_title_19":{"attribute_name":"タイトルよみ","attribute_value_mlt":[{"subitem_alternative_title":"スイタンカンケイ シュヨウ ノ アタラシイ ソシキ ブンルイ ニ カンレン スル ムチン コウゲン ノ イデンシ ハツゲン キコウ"}]},"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-05-27"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2008-2010年度科学研究費補助金(基盤研究(C))研究成果報告書 課題番号：20590345　研究代表者：米澤傑 (鹿児島大学大学院医歯学総合研究科教授)","subitem_description_type":"Other"},{"subitem_description":"膵胆管系腫瘍の早期発見と悪性度の評価については、MUC1、MUC2、MUC4ならびにMUC5ACの組み合わせ評価が有用であることを示した。最近、我々は、それらのムチンの遺伝子発現がエピジェネティクス機構により制御されていることを報告した。それらエピジェネティクスを含むムチン遺伝子発現機構をトランスレーショナルリサーチにより臨床応用することは、ヒト膵胆管系腫瘍の早期かつ正確な診断に寄与すると期待される。","subitem_description_type":"Other"},{"subitem_description":"The combination of MUC1, MUC2, MUC4 and MUC5AC expression is useful for early detection and evaluation of the potential for malignancy of pancreatobiliary neoplasms. Regarding the mechanism of mucin expression, we have recently reported that expression of the mucin genes is regulated epigenetically in cancer cell lines. A future translational research into mucin gene expression mechanisms, including epigenetics, may provide new tools for early and accurate detection of human pancreatobiliary neoplasms.","subitem_description_type":"Other"}]},"item_8_full_name_2":{"attribute_name":"著者よみ","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"ヨネザワ, スグル"}]}]},"item_8_full_name_3":{"attribute_name":"別言語の著者","attribute_value_mlt":[{"nameIdentifiers":[{}],"names":[{"name":"YONEZAWA, Suguru"}]}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_8_text_24":{"attribute_name":"公開者よみ","attribute_value_mlt":[{"subitem_text_value":"カゴシマ ダイガク"}]},"item_8_text_25":{"attribute_name":"公開者別名","attribute_value_mlt":[{"subitem_text_value":"Kagoshima University"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"20590345"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"米澤, 傑"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"20590345seika.pdf","filesize":[{"value":"455.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"20590345seika.pdf","url":"https://ir.kagoshima-u.ac.jp/record/7702/files/20590345seika.pdf"},"version_id":"fbeec6f1-eb4a-4e25-bdb5-7329516948e6"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"消化器","subitem_subject_scheme":"Other"},{"subitem_subject":"唾液腺","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"膵胆管系腫瘍の新しい組織分類に関連するムチン抗原の遺伝子発現機構","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"膵胆管系腫瘍の新しい組織分類に関連するムチン抗原の遺伝子発現機構"}]},"item_type_id":"8","owner":"3","path":["80"],"pubdate":{"attribute_name":"公開日","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"7702","relation_version_is_last":true,"title":["膵胆管系腫瘍の新しい組織分類に関連するムチン抗原の遺伝子発現機構"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-12-25T07:19:56.106146+00:00"}