@article{oai:ir.kagoshima-u.ac.jp:00007834,
 author = {HAYASHI, Seiichi and OOSHIRO, Zentaro},
 journal = {鹿児島大学水産学部紀要=Memoirs of Faculty of Fisheries Kagoshima University},
 month = {2016-10-28},
 note = {Effects of several enzyme-inhibitors on gluconeogenesis in the eel liver were investigated. 3-Mercaptopicolinic acid, an inhibitor of cytosolic phosphoenolpyruvate carboxykinase, inhibited
gluconeogenesis from lactate and pyruvate by 60 and 76%, respectively. These inhibitions by
3-mercaptopicolinic acid were consistent with the intracellular distribution of phosphoenolpyruvate carboxykinase, of wich distribution in the liver cells was about 60% in cytosole and
about 40% in mitochondria. Although it is known that 3-aminopicolinic acid is an activator
of phosphoenolpyruvate carboxykinase and increases gluconeogenesis in mammalian liver, 3-aminopicolinic acid inhibited phosphoenolpyruvate carboxykinase and gluconeogenesis in the
eel liver.
Cycloserine, an inhibitor of transaminases, inhibited gluconeogenesis from lactate and
pyruvate by 40 and 60%, respectively. These results were coincident with those obtained by
using amino-oxyacetate, which is an inhibitor of transaminases.
Malonate, an inhibitor of succinate dehydrogenase, had no effect on gluconeogenesis.
Fluoro acetate, an inhibitor of malate synthetase, and maleic acid, an inhibitor of transaminase, inhibited slightly gluconeogenesis, but not significantly.},
 pages = {167--171},
 title = {Effects of Several Enzyme-Inhibitors on Gluconeogenesis in the Isolated Liver Cells of Eel, Anguilla japonica},
 volume = {32},
 year = {}
}