{"created":"2023-07-25T08:08:39.626530+00:00","id":8093,"links":{},"metadata":{"_buckets":{"deposit":"910f74a9-bb79-41f4-972c-dd4ca8d60a00"},"_deposit":{"created_by":18,"id":"8093","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"8093"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00008093","sets":["228:230:5167","57:58:59"]},"author_link":["3896","3897","119876","13033","119877","119878","3894","119879","3892","119880","3898","3899","3890","2140"],"item_7_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"35","bibliographicPageStart":"31","bibliographicVolumeNumber":"63","bibliographic_titles":[{"bibliographic_title":"鹿児島大学医学雑誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Medical journal of Kagoshima University","bibliographic_titleLang":"en"}]}]},"item_7_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2011-09-01","subitem_date_issued_type":"Issued"}]},"item_7_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"It is reported that gross classification of hepatocellular carcinoma (HCC) is associated with tumors’ malignant behavior.\nWe studied the characteristics and differences between two types of gross classification of HCCs (i.e. Boundary type:\nsingle nodular HCC; Nonboundary type: single nodular with extranodular growth, confluent multinodular, and invasive\nHCCs) by using MIB-1 labeling index (LI) and tumor volume doubling time (DT).\n　 The DT of 87 HCCs, less than 5 cm in diameter at the start of the observation period, was calculated based on\nultrasonographic images. The natural progression of the lesions were observed during 1 month or more.\nRegarding MIB-1 labeling index (LI) of the 87 lesions, we performed immunohistochemical staining (ABC method) with\nthe MIB-1 monoclonal antibody using paraffin-embedded sections obtained by liver resection. The incidence of micrometastasis in the resected sections and the postoperative recurrence ratio were clearly higher in\nthe nonboundary type (n=19) than in the boundary type (n=68). MIB-1 LI and DT were 12.1 +/- 1.3% (mean +/- SE) and\n274.8 +/- 36.2 days in the boundary type and 14.2 +/- 2.0% and 103.9 +/- 13.4 days in the nonboundary type. A significant\ndifference of DT was noticed between the 2 groups.\n　 These results showed that the nonboundary type HCCs included tumors with rapid growth more than those in the\nboundary type. Calculating DT would assist in distinguishing gross classification preinterventionally and in determining\nsuitable therapy such as liver resection and ablation.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_7_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_7_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"03685063","subitem_source_identifier_type":"PISSN"}]},"item_7_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN00040104","subitem_source_identifier_type":"NCID"}]},"item_7_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"494","subitem_subject_scheme":"NDC"}]},"item_7_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"上野, 真一","creatorNameLang":"ja"},{"creatorName":"UENO, Shinichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"迫田, 雅彦","creatorNameLang":"ja"},{"creatorName":"SAKODA, Masahiko","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"飯野, 聡","creatorNameLang":"ja"},{"creatorName":"IINO, Satoshi","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"蔵原, 弘","creatorNameLang":"ja"},{"creatorName":"KURAHARA, Hiroshi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"南, 幸次","creatorNameLang":"ja"},{"creatorName":"MINAMI, Koji","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"安藤, 慶","creatorNameLang":"ja"},{"creatorName":"ANDOU, Kei","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"又木, 雄弘","creatorNameLang":"ja"},{"creatorName":"MATAKI, Yukou","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"喜島, 裕子","creatorNameLang":"ja"},{"creatorName":"KIJIMA, Yuko","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"前村, 公成","creatorNameLang":"ja"},{"creatorName":"MAEMURA, Kosei","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"大脇, 哲弘","creatorNameLang":"ja"},{"creatorName":"OWAKI, Tetsuhiro","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"北薗, 正樹","creatorNameLang":"ja"},{"creatorName":"KITAZONO, Masaki","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"石神, 純也","creatorNameLang":"ja"},{"creatorName":"ISHIGAMI, Sumiya","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"新地, 洋之","creatorNameLang":"ja"},{"creatorName":"SHINCHI, Hiroyuki","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"夏越, 祥次","creatorNameLang":"ja"},{"creatorName":"NATSUGOE, Shoji","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"AN00040104_v63n2_p31-35.pdf","filesize":[{"value":"916.1 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"AN00040104_v63n2_p31-35.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/8093/files/AN00040104_v63n2_p31-35.pdf"},"version_id":"2913152c-f277-495b-b6ee-433d1a7140eb"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Hepatocellular carcinoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"MIB-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Doubling time","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Gross classification","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"Anatomic resection","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"小肝細胞癌の肉眼型分類からみた腫瘍特性 : 細胞増殖能とDoubling Timeの観点から","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"小肝細胞癌の肉眼型分類からみた腫瘍特性 : 細胞増殖能とDoubling Timeの観点から","subitem_title_language":"ja"},{"subitem_title":"Tumor cell proliferation and doubling time of small nodular hepatocellular carcinoma based on gross classification","subitem_title_language":"en"}]},"item_type_id":"7","owner":"18","path":["59","5167"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-01-06"},"publish_date":"2015-01-06","publish_status":"0","recid":"8093","relation_version_is_last":true,"title":["小肝細胞癌の肉眼型分類からみた腫瘍特性 : 細胞増殖能とDoubling Timeの観点から"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-05-27T05:40:44.174442+00:00"}