{"created":"2023-07-25T08:08:41.357084+00:00","id":8124,"links":{},"metadata":{"_buckets":{"deposit":"e3c6f471-29db-4343-9572-ea3786a1fb5b"},"_deposit":{"created_by":18,"id":"8124","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"8124"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00008124","sets":["57:80"]},"author_link":["39050"],"item_8_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2012-05-31","subitem_date_issued_type":"Collected"}]},"item_8_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"2009-2011年度科学研究費助成事業(科学研究費補助金(基盤研究(B)))研究成果報告書　課題番号：21390435　研究代表者：垣花泰之 (鹿児島大学大学院医歯学総合研究科教授)","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"研究の目的は、ピコ秒パルス光による近赤外時間分解分光法（TRS）を用いた脳内cyt.aa3還元状態モニタリング法の確立である。まず血液ファントムモデルから酸素化、脱酸素化Hbの吸収係数をもとめ、その結果をもとに3波長、6波長TRSのcyt.aa3測定用アルゴリズムを作成した。イヌの体外循環モデル、ブタの心停止モデルを用いて確認したところ、3波長TRSに比べて6波長TRSアルゴリズムは、cyt.aa3のシグナル検出に適していることが確認できた。","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"The purpose of this study is the development of the quantitative measurement of the cerebral cyt.aa3 by near-infrared time-resolved spectroscopy (TRS).\nFirstly, the algorithms of the redox state of cyt.aa3 in 3-wavelength or 6-wavelength TRS system were developed by the absorption coefficient values of oxy- and deoxy-Hb, which were obtained by the study of blood phantom models. Furthermore, the algorithms in 3-wavelength or 6-wavelength TRS system were evaluated by the dog model with cardiopulmonary bypass or the pig model with cardiac arrest. We concluded that the algorithms in 6-wavelength TRS system rather than 3-wavelength are capable of reliably measuring changes in the redox state of cerebral cyt.aa3 during severe conditions such as cardiac arrest.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_8_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"鹿児島大学","subitem_publisher_language":"ja"},{"subitem_publisher":"Kagoshima University","subitem_publisher_language":"en"}]},"item_8_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"494","subitem_subject_scheme":"NDC"}]},"item_8_text_41":{"attribute_name":"科研費番号 ","attribute_value_mlt":[{"subitem_text_value":"21390435"}]},"item_8_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"垣花, 泰之","creatorNameLang":"ja"},{"creatorName":"KAKIHANA, Yasuyuki","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"39050","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"1000020264426","nameIdentifierScheme":"NRID","nameIdentifierURI":" "}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"21390435seika.pdf","filesize":[{"value":"412.9 kB"}],"format":"application/pdf","mimetype":"application/pdf","url":{"label":"21390435seika.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/8124/files/21390435seika.pdf"},"version_id":"6af4d31b-d502-4279-85a4-fa047628aef8"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"周術期管理学","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"近赤外時間分解分光システムを用いた周術期脳障害モニタリング法の開発","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"近赤外時間分解分光システムを用いた周術期脳障害モニタリング法の開発","subitem_title_language":"ja"},{"subitem_title":"Development of perioperative cerebral monitoring system using near-infrared time-resolved spectroscopy","subitem_title_language":"en"}]},"item_type_id":"8","owner":"18","path":["80"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-12-22"},"publish_date":"2014-12-22","publish_status":"0","recid":"8124","relation_version_is_last":true,"title":["近赤外時間分解分光システムを用いた周術期脳障害モニタリング法の開発"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-05-24T00:24:44.701380+00:00"}