{"created":"2023-07-25T08:08:51.382576+00:00","id":8326,"links":{},"metadata":{"_buckets":{"deposit":"721a0d8a-9f06-41f7-ab6b-16665284b06d"},"_deposit":{"created_by":18,"id":"8326","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"8326"},"status":"published"},"_oai":{"id":"oai:ir.kagoshima-u.ac.jp:00008326","sets":["54:92"]},"author_link":["13175","28042","11954"],"item_6_biblio_info_5":{"attribute_name":"収録雑誌名","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-06-25","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"248","bibliographicPageStart":"241","bibliographicVolumeNumber":"25","bibliographic_titles":[{"bibliographic_title":"神経眼科","bibliographic_titleLang":"ja"}]}]},"item_6_date_6":{"attribute_name":"作成日","attribute_value_mlt":[{"subitem_date_issued_datetime":"2008-06-25","subitem_date_issued_type":"Issued"}]},"item_6_description_4":{"attribute_name":"要約(Abstract)","attribute_value_mlt":[{"subitem_description":"従来, 人間の光受容器は赤緑青の3錐体と杆体だけであると考えられていたが, 最近, 新たに視物質メラノプシンを含む神経節細胞 (melanopsin-expressing retinal ganglion cell; mRGC) が発見された. mRGCは生体リズムを調節していると考えられている視交叉上核や瞳孔反射をつかさどっている視蓋前域などに投射していることが知られている. 本研究では, mRGCを他の光受容体と独立に刺激するための多原色光源装置を用いて, mRGC経路の信号が輝度経路や色経路の信号とともにどのように瞳孔反応経路に寄与しているかを調べた. 実験の結果は, 輝度信号とmRGC経路の信号は非線形に結合して瞳孔系に入力していることを示唆している. 一方, 色信号とmRGC経路の信号は, 独立に瞳孔システムに入力していることを示唆していることがわかった.","subitem_description_language":"ja","subitem_description_type":"Other"},{"subitem_description":"A recent study has shown that retinal ganglion cells, which are intrinsically\nphotosensitive in primates, contain the photopigment melanopsin and project to\nthe pupillary control center in the pretectum. The aim of this study was to investigate\nhow signals that are driven by the melanopsin-expressing retinal ganglion\ncells (mRGCs) and by the other visual photoreceptors are able to contribute to\nthe pupillary control mechanism. To independently stimulate the mRGCs from\nthe other photoreceptors, we designed and built a novel multi-primary stimulation\nsystem. With regard to the pupillary response, our results suggest that there is a weak interaction between the \n\n M-L \n\n color signals and the mRGC signals.\nHowever, we also found that there is a strong non-linear interaction between the \n\n M+L \n\n luminance signals and the mRGC signals.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_6_publisher_23":{"attribute_name":"公開者・出版者","attribute_value_mlt":[{"subitem_publisher":"日本神経眼科学会","subitem_publisher_language":"ja"}]},"item_6_relation_32":{"attribute_name":"関連（relation）","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/10024899747","subitem_relation_type_select":"URI"}}]},"item_6_rights_12":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"日本神経眼科学会","subitem_rights_language":"ja"}]},"item_6_source_id_7":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"02897024","subitem_source_identifier_type":"PISSN"}]},"item_6_source_id_9":{"attribute_name":"NII書誌ID","attribute_value_mlt":[{"subitem_source_identifier":"AN1004443X","subitem_source_identifier_type":"NCID"}]},"item_6_subject_15":{"attribute_name":"NDC","attribute_value_mlt":[{"subitem_subject":"491","subitem_subject_scheme":"NDC"}]},"item_6_text_44":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_text_value":"著作権者の許諾を得て公開"}]},"item_6_version_type_14":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"辻村, 誠一","creatorNameLang":"ja"},{"creatorName":"ツジムラ, セイイチ","creatorNameLang":"ja-Kana"},{"creatorName":"Tsujimura, Sei-Ichi","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"塗木, 淳夫","creatorNameLang":"ja"},{"creatorName":"ヌルキ, アツオ","creatorNameLang":"ja-Kana"},{"creatorName":"Nuruki, Atsuo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"湯ノ口, 万友","creatorNameLang":"ja"},{"creatorName":"ユノクチ, カズトモ","creatorNameLang":"ja-Kana"},{"creatorName":"Yunokuchi, Kazutomo","creatorNameLang":"en"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2016-10-28"}],"displaytype":"detail","filename":"AN1004443X_v25n2_p241-248.pdf","filesize":[{"value":"20.9 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN1004443X_v25n2_p241-248.pdf","objectType":"fulltext","url":"https://ir.kagoshima-u.ac.jp/record/8326/files/AN1004443X_v25n2_p241-248.pdf"},"version_id":"8f7024e1-378c-4531-8318-1a1d8de4b850"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"melanopsin","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"pupil","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"luminance","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"color","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"メラノプシンを含む神経節細胞の瞳孔系への寄与 : 多原色光源による検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"メラノプシンを含む神経節細胞の瞳孔系への寄与 : 多原色光源による検討","subitem_title_language":"ja"},{"subitem_title":"メラノプシン オ フクム シンケイセツ サイボウ ノ ドウコウケイ エノ キヨ : タゲンショク コウゲン ニヨル ケントウ","subitem_title_language":"ja-Kana"},{"subitem_title":"Pupil Response to Melanopsin-Expressing Retinal Ganglion Cells Studied with a Multi-Primary Illumination System","subitem_title_language":"en"}]},"item_type_id":"6","owner":"18","path":["92"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-01-13"},"publish_date":"2015-01-13","publish_status":"0","recid":"8326","relation_version_is_last":true,"title":["メラノプシンを含む神経節細胞の瞳孔系への寄与 : 多原色光源による検討"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2024-02-07T07:13:41.434752+00:00"}