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実験的ラット口腔癌発生におよぼす遺伝的要因 : 付・4NQO誘発ラット口腔癌について
http://hdl.handle.net/10232/343
http://hdl.handle.net/10232/343433e7503-5fc7-44cd-b250-eb585c634841
名前 / ファイル | ライセンス | アクション |
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KJ00000165760.pdf (3.2 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||||||
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公開日 | 2015-06-04 | |||||||||||||
タイトル | ||||||||||||||
タイトル言語 | ja | |||||||||||||
タイトル | 実験的ラット口腔癌発生におよぼす遺伝的要因 : 付・4NQO誘発ラット口腔癌について | |||||||||||||
タイトル | ||||||||||||||
タイトル言語 | en | |||||||||||||
タイトル | Genetic background of susceptibility to expermental oral carcinoma in rats with an overview on studies of 4NQO-induced carcinoma | |||||||||||||
著者 |
北野, 元生
× 北野, 元生
× 波多野, 浩道
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言語 | ||||||||||||||
言語 | jpn | |||||||||||||
資源タイプ | ||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
資源タイプ | departmental bulletin paper | |||||||||||||
要約(Abstract) | ||||||||||||||
内容記述タイプ | Other | |||||||||||||
内容記述 | The genetic background in relation to the susceptibility to experimental oral carcinogenesis in rats was reviewed. As an experimental model, 4-nitroquinoline 1-oxide (4 NQO)-induced rat carcinoma is thought to be excellent. Because it demonstrates obvious organtropic, species and straas specificity in its carcinogenesis. Administration of 4 NQO-solution as drinking water produces oral carcinomas in rats with a high incidence. We described strain differences on susceptibility to 4 NQO-induced rat carcinoma especially of the tongue concerning 1) enzymal activity of 4 NQO metabolism, 2) 4-hydroxyaminoquinoline 1-oxide (4 HAQO)-DNA adduct formation (4 HAQO is the proximate carcinogenic derivative from 4 NQO), 3) DNA repair processes, and 4) immunological response comparing various strains of rats, to clarify the genetic controls on the experimental carcinogenesis in rats. | |||||||||||||
内容記述言語 | en | |||||||||||||
収録雑誌名 |
ja : 鹿児島大学歯学部紀要 巻 11, p. 35-55, 発行日 1991-03-26 |
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作成日 | ||||||||||||||
日付 | 1991-03-26 | |||||||||||||
日付タイプ | Issued | |||||||||||||
ISSN | ||||||||||||||
収録物識別子タイプ | PISSN | |||||||||||||
ISSN | 0389-7834 | |||||||||||||
NII書誌ID(雑誌) | ||||||||||||||
収録物識別子タイプ | NCID | |||||||||||||
NC ID | AN0035442X | |||||||||||||
出版タイプ | ||||||||||||||
出版タイプ | VoR | |||||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
NDC | ||||||||||||||
主題Scheme | NDC | |||||||||||||
主題 | 497 | |||||||||||||
NIIsubject | ||||||||||||||
主題言語 | ja | |||||||||||||
主題Scheme | Other | |||||||||||||
主題 | 歯学 | |||||||||||||
公開者・出版者 | ||||||||||||||
出版者言語 | ja | |||||||||||||
出版者 | 鹿児島大学 | |||||||||||||
公開者・出版者 | ||||||||||||||
出版者言語 | en | |||||||||||||
出版者 | Kagoshima University |