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Concordance of CAP-RAST responses for food and indoor allergens between sibling pairs with atopic dermatifis
http://hdl.handle.net/10232/8337
http://hdl.handle.net/10232/833708ec23cb-4f6d-4ce8-b0df-bd8792c3f90a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Tsuji.pdf (1.1 MB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2012-01-27 | |||||
| タイトル | ||||||
| タイトル | Concordance of CAP-RAST responses for food and indoor allergens between sibling pairs with atopic dermatifis | |||||
| タイトル言語 | en | |||||
| 著者 |
TSUJI, Mayumi
× TSUJI, Mayumi× KORIYAMA, Chihaya× INABA, Yoichi× AKIBA, Suminori |
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| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | atopic dermatitis | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | food allergy | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | indoor allergy | |||||
| キーワード | ||||||
| 主題言語 | en | |||||
| 主題Scheme | Other | |||||
| 主題 | siblings | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 要約 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Aim: To examine the concordance of positive response to food and indoor allergens between siblings with atopic dermatitis (AD) and factors related to their response to allergens. Methods: Study subjects were 338 Japanese children (169 sibling pairs) diagnosed with AD. A questionnaire was administered to the patients’parents to collect information on medical history and environmental factors for both the patients and the parents in June and July, 2006. The questionnaire asked about the allergic disease histories of the patients’ parents, the patients’ birth weight, way of feeding, and weaning age, the presence of pets in the home, and other environmental factors, including parents’ smoking and alcohol drinking habits. Sera from patients were subjected to CAP radio-allergosorbent test (CAP-RAST) to examine responses to 8 food (egg, cow’s milk, soybean, peanut, sesame, wheat, buckwheat, and rice) and 2 indoor (house dust and mite) allergens. Results: Positive reactions to egg, cow’s milk, wheat, sesame, peanut, and soybean were found in 48% (160/335), 21% (70/334), 14% (46/333), 14% (38/280), 10% (28/285), and 8% (28/333) of children, respectively. Less than 6% of the children were positive for allergies to buckwheat and rice. The frequencies of positive response to house dust and to mites were 46% (105/228) and 47% (106/227), respectively. We examined Spearman’s rank correlation coefficients among all CAP-RAST scores for first- and second-born children, separately. There were significant and strong positive associations among CAP-RAST scores of oil seeds (soybean, peanut, and sesame), and all of their correlation coefficients were higher than 0.700. In the next step, we examined the Spearman’s rank correlation coefficient between the first-and second-born children. There were significant associations between sibling’s CAP-RAST scores for some of the same food allergens, cow’s milk (r = 0.178), soybean (r = 0.227), peanut (r = 0.166), sesame (r = 0.186), and wheat (r = 0.192). We observed more than 0.25 of correlation coefficients among CAP-RAST responses of the first-born children’s soybean and peanut, and the second-born children’s soybean and sesame except the combination of the same allergen. Conclusion: The concordance for allergen-specific positive response between siblings was observed only for oil seeds in this study. | |||||
| 内容記述言語 | en | |||||
| 収録雑誌名 |
ja : 鹿児島大学医学雑誌 en : Medical journal of Kagoshima University 巻 59, 号 3, p. 37-47, 発行日 2008-01-01 |
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| 作成日 | ||||||
| 日付 | 2008-01-01 | |||||
| 日付タイプ | Issued | |||||
| ISSN | ||||||
| 収録物識別子タイプ | PISSN | |||||
| ISSN | 03685063 | |||||
| NII書誌ID（雑誌） | ||||||
| 収録物識別子タイプ | NCID | |||||
| NC ID | AN00040104 | |||||
| 出版タイプ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| NDC | ||||||
| 主題Scheme | NDC | |||||
| 主題 | 490 | |||||
| 公開者・出版者 | ||||||
| 出版者 | 鹿児島大学 | |||||
| 出版者言語 | ja | |||||
| 公開者・出版者 | ||||||
| 出版者 | Kagoshima University | |||||
| 出版者言語 | en | |||||
