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  1. 掲載誌一覧
  2. 鹿児島大学医学雑誌
  3. vol.47(Suppl.2)
  1. 医歯学総合研究科
  2. 鹿児島大学医学会
  3. 鹿児島大学医学雑誌

A Case Report of Unusual Malignant Lymphoma Possibly Derived from Spleen

http://hdl.handle.net/10232/18334
http://hdl.handle.net/10232/18334
cd364083-c732-4d78-8a81-39f3b110a799
名前 / ファイル ライセンス アクション
AN00040104_v47s2_p147-154.pdf AN00040104_v47s2_p147-154.pdf (6.5 MB)
Item type 紀要論文 / Departmental Bulletin Paper(1)
公開日 2013-06-11
タイトル
タイトル A Case Report of Unusual Malignant Lymphoma Possibly Derived from Spleen
著者 MAEDA, Kunihiko

× MAEDA, Kunihiko

WEKO 120331

MAEDA, Kunihiko

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MATSUDA, Mikio

× MATSUDA, Mikio

WEKO 120332

MATSUDA, Mikio

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NAGASHIMA, Ryu-ichi

× NAGASHIMA, Ryu-ichi

WEKO 120333

NAGASHIMA, Ryu-ichi

Search repository
IMAI, Yutaka

× IMAI, Yutaka

WEKO 120334

IMAI, Yutaka

Search repository
著者よみ
姓名 マエダ, クニヒコ
著者よみ
姓名 マツダ, ミキオ
著者よみ
姓名 ナガシマ, リュウイチ
著者よみ
姓名 イマイ, ユタカ
別言語の著者
姓名 前田, 邦彦
別言語の著者
姓名 松田, 幹夫
別言語の著者
姓名 長嶋, 隆一
別言語の著者
姓名 今井, 大
言語
言語 eng
キーワード
主題Scheme Other
主題 DBB42
キーワード
主題Scheme Other
主題 CD19
キーワード
主題Scheme Other
主題 immunoblasts
キーワード
主題Scheme Other
主題 marginal zone
キーワード
主題Scheme Other
主題 indolent lymphoma and immunohistochemistry
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
資源タイプ departmental bulletin paper
要約(Abstract)
内容記述タイプ Other
内容記述 A Trial of Application of the Updated Kiel Classification to Extranodal Malignant Lymphomas with Advice of K. Lennert and AC Feller : Proceedings of the Second Seminar on Malignant Lymphoma in Kagoshima, Japan. April 13 - 15, 1994
要約(Abstract)
内容記述タイプ Other
内容記述 We have encountered a case with unusual type of lymphoma possibly originating in spleen. The case was a 58 years old Japanese male. Clinically he exhibited marked hepato-splenomegaly, no systemic enlargement of lymph nodes (LNs) except for splenic hilar nodes, liver dysfunctions and appearance of a few atypical lymphoid cells in peripheral blood (PB). Splenectomy, lymphadenectomy of the splenic hilar nodes and the wedged-biopsy of liver were performed for histological diagnosis as well as microscopic examinations of bone marrow (BM) and PB. The enlarged spleen (1,200g) displayed diffuse proliferation of immunoblastic cells with prominent plasmacytic differentiation, especially in cords of red pulps and
marginal zone of white pulps. These cells revealed immunoreactivity for DBB42, CD19 but minimal reactivity for CD20. Monotypic light chain of immunoglobulins (λ) and bitypic heavy chains (γ and μ) were also detected in their cytoplasms. These cells infiltrated exclusively in sinuses of splenic hilar LNs, in sinusoid of liver and scatteredly in BM. Many T-cells incuding some transformed cells also infiltrated into the hepatic sinusoid, BM and splenic white pulp. Atypical lymphocytes appeared in PB did not show villous projections as far as we examined. The patient keeps disease-free condition after splenectomy without any chemotherapy except for transient thrombocytopenia. The morphological and immuno-cytochemical features of the major proliferating cells indicated that they were corresponding to the terminal stage in B-cell differentiation. These cellular characteristics and the less aggressive chinical behavior suggested us a variant of lymphoplasmacytic lymphoma (polymorphic subtype) possibly derived from spleen as a possible diagnosis. There were, however, some discrepancies between this case and the previous reported cases especially on the distribution pattern of the lymphoma cells in spleen, liver, LNs and BM and on the accompanying T-cell proliferation. Large cell lymphoma arisiag from marginal zone and microvillous lymphoma should be considered for the differential diagnosis.
収録雑誌名 鹿児島大学医学雑誌=Medical journal of Kagoshima University

巻 47, 号 Suppl. 2, p. 147-154
作成日
日付 1995-11-30
ISSN
収録物識別子タイプ ISSN
ISSN 03685063
NII書誌ID(雑誌)
収録物識別子タイプ NCID
NC ID AN00040104
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
NDC
主題Scheme NDC
主題 490
公開者・出版者
出版者 鹿児島大学
公開者よみ
公開者よみ カゴシマ ダイガク
公開者別名
公開者別名 Kagoshima University
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