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Streptococcus intermediusの感染に関与する付着機構
http://hdl.handle.net/10232/4860
http://hdl.handle.net/10232/48600961dfc4-e47a-413e-935e-2212461691ed
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
28-10.pdf (176.3 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2015-01-13 | |||||||||
| タイトル | ||||||||||
| タイトル | Streptococcus intermediusの感染に関与する付着機構 | |||||||||
| タイトル言語 | ja | |||||||||
| タイトル | ||||||||||
| タイトル | Adherence mechanism in infection of Streptococcus intermedius | |||||||||
| タイトル言語 | en | |||||||||
| 著者 |
山口, 泰平
× 山口, 泰平
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| 言語 | ||||||||||
| 言語 | jpn | |||||||||
| キーワード | ||||||||||
| 主題言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | Streptococcus intermedius | |||||||||
| キーワード | ||||||||||
| 主題言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | fimbriae | |||||||||
| キーワード | ||||||||||
| 主題言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | saliva agglutinin | |||||||||
| キーワード | ||||||||||
| 主題言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | adherence | |||||||||
| キーワード | ||||||||||
| 主題言語 | en | |||||||||
| 主題Scheme | Other | |||||||||
| 主題 | albumin | |||||||||
| 資源タイプ | ||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
| 資源タイプ | departmental bulletin paper | |||||||||
| 要約 | ||||||||||
| 内容記述タイプ | Other | |||||||||
| 内容記述 | The first step of bacterial infection is adherence to host tissue. Streptococcus intermedius is a significant component in the normal oral floor and one of the most common causes of oral and systemic pyogenic infections. This organism possessed particular-type fimbriae expanded from the cell surface. Molecular biological approach demonstrated that the appendages were associated with bacterial aggregation and adherence mediated by human saliva. Receptor molecule on the host was purified and identified with saliva agglutinin/DMBTl/gp-340 from whole saliva. However, bacterial aggregation titer was not directly associated with adherence titer nor clinical data concerning dental caries among five healthy male. Thereafter, the molecule that inhibited the bacterial adherence to immobilized saliva agglutinin was identified with human albumin in human saliva. In the high concentration conditions, albumin worked as inhibitor, but in the low concentration conditions, as enhancer. The functional domain was located within the area from third exon to sixth exon using a valiant albumin clone derived from human fiver. The concentration of agglutinin and albumin in whole saliva was widely varied among individuals. These molecules could carefully control the composition of oral flora in individuals. I expect that further research could produce a novel and effective preventive approach for bacterial infection in systemic disease as well as oral disease. | |||||||||
| 内容記述言語 | en | |||||||||
| 収録雑誌名 |
ja : 鹿児島大学歯学部紀要 巻 28, p. 27-37, 発行日 2008-03-26 |
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| 作成日 | ||||||||||
| 日付 | 2008-03-26 | |||||||||
| 日付タイプ | Issued | |||||||||
| ISSN | ||||||||||
| 収録物識別子タイプ | PISSN | |||||||||
| ISSN | 03897834 | |||||||||
| NII書誌ID（雑誌） | ||||||||||
| 収録物識別子タイプ | NCID | |||||||||
| NC ID | AN0035442X | |||||||||
| 出版タイプ | ||||||||||
| 出版タイプ | VoR | |||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
| NDC | ||||||||||
| 主題Scheme | NDC | |||||||||
| 主題 | 497 | |||||||||
| 公開者・出版者 | ||||||||||
| 出版者 | 鹿児島大学 | |||||||||
| 出版者言語 | ja | |||||||||
| 公開者・出版者 | ||||||||||
| 出版者 | Kagoshima University | |||||||||
| 出版者言語 | en | |||||||||
