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  1. 医歯学総合研究科
  2. 医歯学総合研究科・博士論文

Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study.

http://hdl.handle.net/10232/00030355
http://hdl.handle.net/10232/00030355
82e99534-cf8f-4321-819d-bb1f37083ec7
名前 / ファイル ライセンス アクション
Diss_田口_宏樹_ISK484_2018.pdf Diss_田口_宏樹_ISK484_2018 (502.1 kB)
license.icon
Abstract_田口_宏樹_4511800031_2018.pdf Abstract_田口_宏樹_4511800031_2018 (93.9 kB)
Result_Taguchi_Hiroki_isk_484_2018.pdf Result_Taguchi_Hiroki_isk_484_2018 (953.0 kB)
Comments_Taguchi_Hiroki_isk_484_2018.pdf Comments_Taguchi_Hiroki_isk_484_2018 (432.4 kB)
Item type 学位論文 / Thesis or Dissertation(1)
公開日 2018-12-04
タイトル
タイトル Helicobacter pylori eradication improves the quality of life regardless of the treatment outcome: A multicenter prospective cohort study.
別言語のタイトル
その他のタイトル Helicobacter pylori除菌治療は治療結果にかかわらず生活の質を改善する : 多施設共同前方視的コホート研究
著者 田口, 宏樹

× 田口, 宏樹

WEKO 132187

田口, 宏樹

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著者よみ
姓名 タグチ, ヒロキ
別言語の著者
姓名 TAGUCHI, Hiroki
言語
言語 eng
キーワード
主題言語 en
主題Scheme Other
主題 dyspepsia
キーワード
主題言語 en
主題Scheme Other
主題 epigastralgia
キーワード
主題言語 en
主題Scheme Other
主題 eradication treatment
キーワード
主題言語 en
主題Scheme Other
主題 Helicobacter pylori
キーワード
主題言語 en
主題Scheme Other
主題 mental component summary
キーワード
主題言語 en
主題Scheme Other
主題 physical component summary
キーワード
主題言語 en
主題Scheme Other
主題 quality of life
資源タイプ
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
資源タイプ doctoral thesis
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
要約(Abstract)
内容記述タイプ Other
内容記述 Helicobacter pylori (Hp) eradication is recommended for improving the quality of life (QOL) of patients with epigastric symptoms, especially reflux and dyspepsia. However, no reports have investigated the improvement of QOL after the eradication of Hp irrespective of epigastric symptoms. The aim of this study was to investigate the improvement in the QOL after the eradication of Hp irrespective of epigastric symptoms, and evaluate the factors associated with an improved QOL after the eradication of Hp.
This prospective cohort study was performed at 15 referral institutions from September 2013 to December 2014. The patients’ QOL and epigastric symptoms were evaluated before and after the eradication of Hp using the 8-item Short-Form Health Survey (SF-8) and the modified Frequency Scale for the Symptoms of Gastroesophageal Reflux Disease, respectively.
One hundred sixty-five of 184 Hp-infected patients underwent Hp eradication treatment. The treatment was successful in 82.4% (136/165) of the cases. One hundred sixty of the 165 Hp-infected patients were eligible for inclusion in the QOL analysis. In the indices of QOL on the SF-8, the scores on both the mental component summary (MCS) and the physical component summary (PCS) were found to have significantly improved after the eradication of Hp. However, the epigastric symptoms before the eradication of Hp were not correlated with either the MCS or PCS. A low QOL value before the eradication of Hp was the factor what was most strongly associated with the improvement in the QOL.
The eradication of Hp improved the QOL, regardless of the outcome of the treatment, especially in patients who had an impaired QOL before the eradication.
収録雑誌名 Medicine

巻 96, 号 52
ISSN
収録物識別子タイプ ISSN
収録物識別子 00257974
DOI
識別子タイプ DOI
DOI 10.1097/MD.0000000000009507
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
NDC
主題Scheme NDC
主題 492
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文全文
ファイル(説明)
内容記述タイプ Other
内容記述 博士論文要旨
ファイル(説明)
内容記述タイプ Other
内容記述 最終試験結果の要旨
ファイル(説明)
内容記述タイプ Other
内容記述 論文審査の要旨
公開者・出版者
出版者 鹿児島大学
公開者・出版者
出版者 Wolters Kluwer
公開者よみ
公開者よみ カゴシマ ダイガク
公開者別名
公開者別名 Kagoshima University
備考
備考 【指導教員:井戸章雄】
date.appl
【学位申請日】2018/8/1
学位名
学位名 博士(医学)Doctor of Philosophy in Medical Science
学位授与機関
学位授与機関識別子Scheme kakenhi
学位授与機関識別子 17701
学位授与機関名 鹿児島大学
学位授与年月日
学位授与年月日 2018-11-20
学位授与番号
学位授与番号 甲総研第484号
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